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>Journals >Revista Mexicana de Pediatría >Year 2001, Issue 1


Martínez-Jiménez NB, Maza-Toledo AA, López-Jiménez CC, Ortiz-Méndez VM
Answer to the treatment of the bronchiolitis with natural epinephrine (levogyral) inhaled
Rev Mex Pediatr 2001; 68 (1)

Language: Español
References: 11
Page: 5-7
PDF: 41.40 Kb.


Full text




ABSTRACT

The benefitial effects of inhaled racemic epinephrine in pediatric patients with bronchiolitis, has been well demonstrated in several studies. This drug is not available in our country, neither there are studies about its effects in bronchiolitis. Levogire epinephrine (aquous 1:1000) is available nationwide and its efficacy for the treatment of bronchiolitis is also well documented; besides it is more effective than racemic epinephrine and with less side effects. In order to corroborate the former, we decided to study a group of patients with bronchiolitis. Fifty patients with clinical diagnosis of bronchiolitis were studied. After diagnosis was stablished, each one received aquous epinephrine at a dose of 0.25 mg/kg of body weight, through a jet nebulizer. Clinical signs of respiratory distress were evaluated with the Downes score, before and after each dose of epinephrine. All patients received a total of three doses, administered 24 h appart. One patient had to be excluded because of the severity of symptoms, for which he had to be admitted to the emergency room. The clinical response of the remaining 49 patients was good. Statistical analysis was made with the Wilcoxon test, comparing the initial and final score on days 1, 2 and 3; and initial score on day 1 with final score on day 3. p value was ‹ 0.05.


Key words: Bronchiolitis, levogire epinephrine, respiratory distress.


REFERENCIAS

  1. Orenstein DM. Bronchiolitis. In: Behrman RE, Kliegman RM, Harbin AM: Nelson textbook of pediatrics. 15th Ed. WB Saunders Co. Philadelphia 1996; 1211-13.

  2. Bronchiolitis. In: Dworkin PH. Pediatrics. 3rd Ed. Williams & Wilkins. Baltimore 1996: 296-97.

  3. Black-Payne C. Bronchiolitis. In: Hilman BC: Pediatric respiratory disease. Diagnosis and treatment. 3rd Ed. WB Saunders Co. Philadelphia 1993: 205-17.

  4. Cressman WR, Myer CM. Diagnóstico y tratamiento de crup y epiglotitis. Clin Pediat N Am 1994; 2: 313-23.

  5. Kritjarisson S, Lodrup Carlsen KC, Wennergren G et al. Nebulized racemic adrenaline in the treatment of acute bronchiolitis in infants and toddlers. Arch Dis Child 1993; 69: 650-54.

  6. Waisman Y, Kelin BL, Douglas A. Prospective randomized double blind study comparing L-epinephrine and racemic epinephrine aerosols in the treatment of laringotracheitis (croup). Pediatrics 1992; 89: 302-6.

  7. Nutman J, Deakins K, Baldesatre K. Prospective randomized double blind study comparing racemic epinephrine and L-epinephrine in the treatment of post-intubation laryngeal edema. Crit Care Med 1994; 22: 1591-94.

  8. McDonough AJ. The use of steroids and nebulized adrenaline in the treatment of viral croup over a seven year period at a district hospital. Anaesth Int Care 1994; 22: 175-78.

  9. Sánchez I, De Koster J, Powell RE, Wolstein R, Chernick V. Effect of racemic epinephrine and salbutamol on clinical score and pulmonary mechanics in infants with bronchiolitis. J Pediatr 1993; 122: 145-51.

  10. Menon K, Sutcliffe T, Klaussen TP. A randomized trial comparing the efficacy of epinephrine with salbutamol in the treatment of acute bronchiolitis. J Pediatr 1995; 126: 1004-7.

  11. Maza-Toledo A. Empleo de fármacos por inhalación. Rev Mex Pediatr 1998; 65: 182-86.






>Journals >Revista Mexicana de Pediatría >Year 2001, Issue 1
 

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