medigraphic.com
ISSN 2395-8723 (Electronic)
ISSN 1405-888X (Print)
TIP Revista Especializada en Ciencias Químico-Biológicas

2020, Number 1

<< Back Next >>

TIP Rev Esp Cienc Quim Biol 2020; 23 (1)

Optimization of ultrasound-assisted extraction of phenolic compounds from Justicia spicigera Schltdl. by response surface methodology

Hernández-Rodríguez S, Quiroz-Reyes CN, Ramírez-Ortiz ME, Ronquillo-de Jesús E, Aguilar-Méndez MÁ

Language: Spanish
References: 25
Page: 1-7
PDF size: 490.66 Kb.


ABSTRACT

The interest in the study of polyphenols has grown considerably in recent years due to its high capacity to scavenge free radicals associated with various diseases. For this reason, the aim of this work was to obtain and characterize phenolic compounds from Justicia spicigera Schltdl by ultrasound-assisted extraction. The extracts were characterized in terms of the total phenolic content (Folin-Ciocalteu method), antioxidant activity (ferric-reducing/antioxidant power) and free radical scavenging activity (2,2-diphenyl-1-picrylhydrazyl free radical method). The response surface methodology (RSM) was used to evaluate the effect of the solvent (water/ethanol) and the extraction time, on the total phenolic content and antioxidant properties. The analysis of variance (ANOVA) indicated that the concentration of water in the solvent mixture significantly affected the yield of the compounds, as well as the antioxidant and antiradical activities. According to the RSM, the optimal extraction conditions are 25% water in the solvent mixture and a sonication time of 16 min.


REFERENCES

  1. Alonso-Castro, A. J., Ortiz-Sánchez, E., Domínguez, F., Arana-Argáez, V., Juárez-Vázquez, M. C., Chávez, M., Carranza-Álvarez, C., Gaspar-Ramírez, O., Espinosa- Reyes, G., López-Toledo, G., Ortiz-Andrade, R. & García- Carrancá, A. (2012). Antitumor and immunomodulatory effects of Justicia spicigera Schltdl. (Acanthaceae). Journal of Ethnopharmacology, 141, 888−894. https://doi. org/10.1016/j.jep.2012.03.036.

  2. Benzie, I. & Strain, J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: The FRAP Assay. Analytical Biochemistry, 239, 70−76. https:// doi.org/10.1006/abio.1996.0292.

  3. Cai, L., Chen, B., Yi, F. & Zou, S. (2019). Optimization of extraction of polysaccharide from dandelion root by response surface methodology: Structural characterization and antioxidant activity. International Journal of Biological Macromolecules, 140, 907−919. https://doi.org/10.1016/j. ijbiomac.2019.08.161.

  4. Da Porto, C., Porretto, E. & Decorti, D. (2013). Comparison of ultrasound-assisted extraction with conventional extraction methods of oil and polyphenols from grape (Vitis vinifera L.) seeds. Ultrasonics Sonochemistry, 20, 1076−1080. https://doi.org/10.1016/j.ultsonch.2012.12.002.

  5. Davey, M. W., Montagu, M. V., Inzé, D., Sanmartin, M., Kanellis, A., Smirnoff, N., Benzie, I. J. J., Strain, J. J., Favell, D. & Fletcher, J. (2000). Plant L-ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing. Journal of the Science of Food and Agriculture, 80, 825−860. https://doi.org/10.1002/(SICI)1097- 0010(20000515)80:7<825::AID-JSFA598>3.0.CO;2-6.

  6. Fernández-Pomares, C., Juárez-Aguilar, E., Domínguez-Ortiz, M. A., Gallegos-Estudillo, J., Herrera-Covarrubias, D., Sánchez-Medina, A., Aranda-Abreu, G. E., Manzo, J. & Hernández, M. E. (2018). Hydroalcoholic extract of the widely used Mexican plant Justicia spicigera Schltdl. exerts a cytostatic effect on LNCaP prostate cancer cells. Journal of Herbal Medicine, 12, 66−72. https://doi.org/10.1016/j. hermed.2017.09.003.

  7. García-Ríos, R. I., Mora-Pérez, A., González-Torres, D., Carpio- Reyes, R. J. & Soria-Fregozo, C. (2019). Anxiolytic-like effect of the aqueous extract of Justicia spicigera leaves on female rats: A comparison to diazepam. Phytomedicine, 55, 9−13. DOI: 10.1016/j.phymed.2018.07.007.

  8. González -Trujano, M. E., Domínguez, F., Pérez-Ortega, G., Aguillón, M., Martínez-Vargas, D., Almazán-Alvarado, S. & Martínez, A. (2017). Justicia spicigera Schltdl. and kaempferitrin as potential anticonvulsant natural products. Biomedicine & Pharmacotherapy, 92, 240−248. https:// doi.org/10.1016/j.biopha.2017.05.075.

  9. Kabir, F., Tow, W. W., Hamauzu, Y., Katayama, S., Tanaka, S. & Nakamura, S. (2015). Antioxidant and cytoprotective activities of extracts prepared from fruit and vegetable wastes and by-products. Food Chemistry, 167, 358−362. https://doi.org/10.1016/j.foodchem.2014.06.099.

  10. Kelly, N. P., Kelly, A. L. & O’Mahony, J. A. (2019). Strategies for enrichment and purification of polyphenols from fruitbased materials. Trends in Food Science & Technology, 83, 248−258. https://doi.org/10.1016/j.tifs.2018.11.010.

  11. Khalifa, I., Zhu, W., Li, K.-k. & Li, C.-m. (2018). Polyphenols of mulberry fruits as multifaceted compounds: Compositions, metabolism, health benefits, and stability-A structural review. Journal of Functional Foods, 40, 28−43. https:// doi.org/10.1016/j.jff.2017.10.041.

  12. Liu, X., Luo, G., Wang, L. & Yuan, W. (2019). Optimization of antioxidant extraction from edible brown algae Ascophyllum nodosum using response surface methodology. Food and Bioproducts Processing, 114, 205−215. https://doi. org/10.1016/j.fbp.2019.01.003.

  13. Majidinia, M., Bishayeeb, A. & Yousefic, B. (2019). Polyphenols: Major regulators of key components of DNA damage response in cancer. DNA Repair, 82, 102679. https://doi. org/10.1016/j.dnarep.2019.102679.

  14. Mkaouar, S., Bahloul, N., Gelicus, A., Allaf, K. & Kechaou, N. (2015). Instant controlled pressure drop texturing far intensifying ethanol solvent extraction of olive (Olea europaea) leaf polyphenols. Separation and Purification Technology, 145, 139−146. https://doi.org/10.1016/j. seppur.2015.03.014.

  15. Molyneux, P. (2004). The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin Journal of Science Technology, 26, 211−219.

  16. Montgomery, C. D. (2005). Diseño y análisis de experimentos. 2a ed. Limusa Wiley. Ciudad de México.

  17. Ortiz-Andrade, R., Cabañas-Wuan, A., Arana-Argáez, V. E., Alonso-Castro, A. J., Zapata-Bustos, R., Salazar-Olivo, L. A., Domínguez, F., Chávez, M., Carranza-Álvarez, C. & García-Carrancá, A. (2012). Antidiabetic effects of Justicia spicigera Schltdl. (Acanthaceae). Journal of Ethnopharmacology, 143, 455−462. https://doi. org/10.1016/j.jep.2012.06.043.

  18. Paciolla, C., Fortunato, S., Dipierro, N., Paradiso, A., De Leonardis, D., Mastropasqua, L. & de Pinto, M. C. (2019). Vitamin C in plants: from functions to biofortification. Antioxidants, 8, 519. https://doi.org/10.3390/antiox8110519.

  19. Stavrou, I. J., Christou, A. & Kapnissi-Christodoulou, C. P. (2018). Polyphenols in carobs: A review on their composition, antioxidant capacity and cytotoxic effects, and health impact. Food Chemistry, 269, 355−374. https:// doi.org/10.1016/j.foodchem.2018.06.152.

  20. Takaidza, S., Mtunzi, F. & Pillay, M. (2018). Analysis of the phytochemical contents and antioxidant activities of crude extracts from Tulbaghia species. Journal of Traditional Chinese Medicine, 38, 272−279. https://doi.org/10.1016/j. jtcm.2018.04.005.

  21. Wang, Y., Huang, S., Shao, S., Qian, L. & Xu, P. (2012). Studies on bioactivities of tea (Camellia sinensis L.) fruit peel extracts: Antioxidant activity and inhibitory potential against α-glucosidase and α-amylase in vitro. Industrial Crops and Products, 37, 520−526. https://doi.org/10.1016/j. indcrop.2011.07.031.

  22. Waterhouse, A. L. (2002). Determination of total phenolics. En: Current Protocols in Food Analytical Chemistry. R.E. Wrolstad (ed.), units I.1.1.1-I1.1.8. John Wiley and Sons. New York. https://doi.org/10.1002/0471142913.fai0101s06.

  23. Wootton-Beard, P. C., Moran A. & Ryan, L. (2011). Stability of the total antioxidant capacity and total polyphenol content of 23 commercially available vegetable juices before and after in vitro digestion measured by FRAP, DPPH, ABTS and Folin-Ciocalteu methods. Food Research International, 44, 217−224. https://doi.org/10.1016/j. foodres.2010.10.033.

  24. Zhang, H., Qi, R. & Mine, Y. (2019). The impact of oolong and black tea polyphenols on human health. Food Bioscience, 29, 55−61. https://doi.org/10.1016/j.fbio.2019.03.009.

  25. Živković, J., Janković, T., Menković, N. & Šavikin, K. (2019). Optimization of ultrasound-assisted extraction of isogentisin, gentiopicroside and total polyphenols from gentian root using response surface methodology. Industrial Crops & Products, 139, 111567. https://doi.org/10.1016/j. indcrop.2019.111567.




2020     |     www.medigraphic.com