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Revista Cubana de Oftalmología

ISSN 1561-3070 (Electronic)
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2020, Number 1

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Rev Cub Oftal 2020; 33 (1)

Confocal microscopy of the cornea in diabetic patients

Gutiérrez CM, Castillo PAC, Ramos LM, Pérez PZ, Ramos PY, Barroso LR
Full text How to cite this article

Language: Spanish
References: 11
Page: 1-12
PDF size: 392.28 Kb.


Key words:

confocal microscopy, cornea, diabetes mellitus.

ABSTRACT

Objective: Identify the morphological characteristics of the corneal epithelium, stroma and endothelium, as well as the cell density of the endothelium by means of confocal microscopy of the cornea in diabetic patients.
Methods: A descriptive comparative study was conducted of 90 eyes: 60 from diabetic patients (30 type 1 and 30 type 2) and 30 from supposedly healthy patients, at Ramón Pando Ferrer Cuban Institute of Ophthalmology from January 2012 to January 2017.
Results: A predominance was found of the male sex (66.7%) among patients with diabetes mellitus type 1 and of the female sex among patients with diabetes mellitus type 2 (60%) and seemingly healthy patients (56.7%). The most common age ranges were 45-54 years for patients with diabetes mellitus type 1 (33.3%) and 55-66 years for patients with diabetes mellitus type 2 (60%) and seemingly healthy patients (40%). Morphology of the corneal epithelium and stroma was normal in 86.7% and 87.3%, respectively. In type 1 diabetic patients there was a predominance of endothelial morphological alterations (73.3%), polymegethism and pleomorphism (73.3% and 56.7%, respectively) and the lowest cell density (2 222.76 cells /mm2).
Conclusions: Absence of morphological alterations of the corneal epithelium and stroma, as well as the presence of polymegethism and pleomorphism were the most common findings.


REFERENCES

  1. Kanski JJ, Ilenon J. Oftalmología Clínica. Madrid: Editorial Elsevier; 2016. p. 167-210.

  2. American Academy of Ophthalmology. Structure and function of the external eye and cornea. En: External Disease and Cornea. Basic and Clinical Science, course 2017-2018. p. 306-8.

  3. Dirección Nacional de Registros Médicos y Estadísticas de salud. Anuario Estadístico de Salud. Ciudad de La Habana: MINSAP: 2017. p. 43.

  4. Rodríguez Rodríguez B. Prevención de ceguera por retinopatía diabética: ¿dónde estamos? Rev Cubana Oftalmol. 2015;28(1):5.

  5. Pei-Yao Ch, Hyman C, Jen-Shang H, Jong W. Decreased density of corneal basal epithelium and subbasal corneal nerve bundle changes in patients with diabetic retinopathy. Am J Ophtalmol; 2006;142(3):488-90.

  6. Hormigó Puertas I, Cárdenas Díaz T, Duperet Carvajal D, Cuan Aguilar Y, Trujillo Fonseca K, Rodríguez Suárez B. Alteraciones corneales en pacientes diabéticos. Rev Cubana Oftalmol. 2016:29(2):2.

  7. Grupcheva C, Malik T, Craig JP, Mc Ghee C. ln vivo confocal microscopy of corneal epithelial. J Cataract Refract Surg. 2001;27:1319-22.

  8. Sang Beom H, Hee Kyung Y, Joon Young H. Influence of diabetes mellitus on anterior segment of the eye. Clin Interv Aging. 2019;14:53-63.

  9. Quadrado M, Popper M, Morgado AM, Murta J, Van B, Jaap A. Corneal Hydration control in diabetes mellitus. Lippincott &Wilkins; 2006: 761-8.

  10. Roszkowska A, Tringali C, Colosi P, Squeri C, Ferreri G. Corneal endothelium evaluation in type I and type ll diabetes mellitus. Italy: University of Messina, Institute of Ophthalmology; 2002:258-61.

  11. Parekh R, Ranganath K, Suresh K, Dharmalingam M. Corneal endothelium count and thickness in diabetes mellitus. Bangalore, India: Nat Inst Anim Physiol. 2006;26:24-6.




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Rev Cub Oftal. 2020;33