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2020, Number 3

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Correo Científico Médico 2020; 24 (3)

Characterization of diabetic patients infected with COVID-19 admitted to the OGR hospital. Torino, Italy

González HM, Osoria MLM, Santines AY, León RL, Almenares GA, Pérez RVR
Full text How to cite this article

Language: Spanish
References: 12
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Key words:

diabetes mellitus, SARS CoV-2, dispensing.

ABSTRACT

Introduction: The development of virulence of SARS CoV-2 has a very close relationship with diabetes mellitus.
Objective: To characterize the diabetic patients infected with COVID-19, admitted to the OGR hospital.
Methods: A descriptive, cross-sectional study was carried out. The universe of study was the totality of patients admitted to the Hospital for COVID-19, OGR. The sample was 38 patients admitted with a diagnosis of diabetes mellitus.
Results: The predominant sex was male, with 55%, and the age group was from 71 to 80 years, with 36.8%. The most frequent comorbidities were high blood pressure with 100%, chronic kidney disease, with 73.7%, obesity, with 76.3%, ischemic heart disease, with 63.1%, chronic obstructive pulmonary disease, with 44, 7%, ICTUS with 21%, and neoplasms with 15.8%. Insulin was used in 63.1% of cases, metformin in 50%, and DPP-4 inhibitors in 34.2% of treated patients. Steroids were prescribed in 100% of cases. The presence of severe pneumonia was observed in 65.8% of patients, oxygen desaturation in 39.5%. 34.2% of the studied patients showed psychological stress, dietary transgressions occurred in 31.6% of the cases. Decompensated patients predominated, with 65.8% of cases on admission. 71% of patients improved the respiratory symptoms, as blood glucose levels were compensated.
Conclusions: Male patients between 71 and 80 years were the most affected. High blood pressure was the most frequent comorbidity. 71% of patients improved respiratory symptoms, as blood glucose levels were compensated.


REFERENCES

  1. American Diabetes Association. Diagnosis and classificationof diabetes mellitus. Diabetes Care. 2014[citado 24 /06/2020];37(Suppl 1):S81-90.Disponible en: https://pubmed.ncbi.nlm.nih.gov/24357215/

  2. International Diabetes Federation.Diabetes Atlas. 9th ed. Brussels: IDF; 2019.

  3. Cui J, Li F, Shi ZL. Origin and evolutionofpathogeniccoronaviruses. Nat Rev Microbiol. 2019[citado 24 /06/2020]; 17: 181-92.Disponible en: https://www.nature.com/articles/s41579-018-0118-9

  4. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomiccharacterisation and epidemiologyof 2019 novel coronavirus: implicationsfor virus origins and receptor binding. Lancet. 2020 [citado 24 /06/2020]; 395: 565-74.Disponible en: https://www.thelancet.com/article/S0140- 6736(20)30251-8/fulltext

  5. Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD .Inhibidores del sistema renina-angiotensina-aldosterona en pacientes con covid-19. N Engl J Med. 2020[citado 24 /06/2020].Disponible en: https://www.intramed.net/contenidover.asp?contenidoid=95880

  6. Hoffmann M, Kleine Weber H, Krüger N, Müller M, Drosten C, Pöhlmann S. The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells. Bio Rxiv. 2020[citado 24 /06/2020].Disponible en: https://www.biorxiv.org/content/10.1101/2020.01.31.929042v1

  7. Chen X, Hu W, Ling J, Mo P, Zhang Y, Jiang Q, et al. Hypertension and Diabetes Delay the Viral Clearance in COVID-19 Patients. Med Rxiv. 2020[citado 28/06/2020].Disponible en: https://www.medrxiv.org/content/10.1101/2020.03.22.20040774v1

  8. Roca Ho H, Riera M, Palau V, Pascual J, Soler MJ. Caracterización de la expresión de ACE y ACE2 287 dentro de diferentes órganos del ratón NOD. Int J Mol Sci. 2017 [citado 15/05 2020];18(3):563.Disponible en: https://pubmed.ncbi.nlm.nih.gov/28273875/

  9. Rao S, Lau A, So HC. Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: A Mendelian Randomization analysis highlights tentative relevance of diabetes-related traits. Diabetes Care. 2020[citado 23/06/2020]; 43(7): 1416-1426.Disponible en: https://care.diabetesjournals.org/content/43/7/1416

  10. Fernández C, Rysa J, Almgren P, Nilsson J, Engstrom G, Orho-Melander M, et al. Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality. J Intern Med. 2018[citado 25/04/2020]; 284(4): 377 387.Disponible en: https://onlinelibrary.wiley.com/doi/10.1111/joim.12783

  11. Kulcsar KA, Coleman CM, Beck SE, Frieman MB. La diabetes comórbida da como resultado una desregulación inmune y una mayor gravedad de la enfermedad después de la infección por MERS-CoV. JCI Insight. 2019; 4 (20).

  12. Maddaloni E, Buzzetti R. Covid-19 y diabetes mellitus: desvelando la interacción de dos pandemias. Diabetes Metab Res Rev. 2020[citado 31/03/2020].Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1002/dmrr.3321




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Correo Científico Médico. 2020;24