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2021, Number 2

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Med Int Mex 2021; 37 (2)

Clinical and microbiological characteristics of patients with diabetic foot

Mendoza-Martínez P, Almeda-Valdés P, Janka-Zires M, Gómez-Pérez FJ
Full text How to cite this article

Language: Spanish
References: 22
Page: 196-211
PDF size: 446.87 Kb.


Key words:

Diabetic food, Syndromes, Ischemia, Morbidity, Osteomyelitis, Amputation, Palpation, Ulcer, Polymicrobial infection.

ABSTRACT

Background: Diabetic foot is a group of syndromes in which neuropathy, ischemia and infection produce tissue injury, morbidity and damage. Osteomyelitis is a frequent complication that, even in 66% of cases, is associated with amputation.
Objective: To know the clinical characteristics and microbiology of osteomyelitis in diabetic foot of bone biopsies at National Institute of Medical Sciences and Nutrition Salvador Zubirán in Mexico City.
Materials and Methods: Ambispective, observational study consisting of a review of the data in the records of patients with a diagnosis of diabetic foot treated at the National Institute of Medical Sciences and Nutrition Salvador Zubirán (Mexico City) between June 2016 and June 2019.
Results: Seventy-seven complete records of patients with a diagnosis of diabetic foot treated for the first time were studied, 43 were men with a median age of 60 years. Fifty-nine patients had ulcers and 14 patients suffered amputation. The variables associated with amputation were male sex (p = 0.05), erythrocyte sedimentation rate (p ‹ 0.0010), C-reactive protein (p = 0.004), leukocytosis (p = 0.001) and the absence of popliteal, posterior tibial and pedial pulses on examination (p = 0.002, 0.002 and 0.0, respectively).
Conclusions: Male patients, with non palpable or diminished pulses of the affected limb, a clinical presentation of a PEDIS 4 ulcer, markers of inflammation present and Charcot deformity require close monitoring, due to the risk associated with amputation.


REFERENCES

  1. Gutiérrez JP, Rivera-Dommarco J, Shamah-Levy T, Villalpando- Hernández S, et al. Encuesta Nacional de Salud y Nutrición 2012. Resultados Nacionales. Cuernavaca, México: Instituto Nacional de Salud Pública, 2012.

  2. Hartemann-Heurtier A. Diabetic foot osteomyelitis. Diabetes and Metabolism. 2008; 34: 87-95. https://doi. org/10.1016/j.diabet.2007.09.005.

  3. Cabeza de Vaca F, Macías A, Álvarez JA, Cuevas A, Ramírez AJ, Ramírez WA. et al. Microbiología del pie diabético determinada por estudio de biopsia. Rev Invest Clín. 2009; 61(4): 281-85.

  4. Lipsky B. Infectious Diseases Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infections. Clinical Infectious Diseases 2012;54(12):132-73. https://doi.org/10.1093/cid/cis346.

  5. Markanday A. Diagnosing Diabetic Foot Osteomyelitis: Narrative Review and a Suggested 2-Step Score-Based Diagnostic Pathway for Clinicians. Open Forum Infectious Diseases. 2014. https://doi.org/10.1093/ofid/ofu060.

  6. Shaper NC. Diabetic foot ulcer classification system for research purposes: a progress report on criteria for including patients in research studies. Diabetes Metab Res Rev. 2004;20 Suppl 1:S90-S95. https://doi.org/10.1002/ dmrr.464.

  7. Blanes J, García-Sánchez JE. Documento de consenso sobre el tratamiento de las infecciones en el pie del diabético. Rev Esp Quimioter 2011; 24 (4): 233-62. https://doi. org/10.1016/j.angio.2011.11.001.

  8. Cadima-Fernández R, Almeda Valdez P, et al. Características Clínicas y Microbiológicas de la Osteomielitis en pacientes con pie diabético en el Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán 2012-2015. Poster presentado en la LV congreso internacional de la Sociedad Mexicana de Nutrición y Endocrinología.

  9. Amstrong David, Lavery Lawrence. Editors. Clinical Care of the Diabetic Foot. 3rd ed. American Diabetes Asociation, 2015.

  10. Ammar-Ibrahim MD, FACS, Chair IDF Diabetic foot stream et al “IDF Clinical Practice Recommendations on the diabetic Foot 2017. International Diabetes Federation, 2017 ISBN: 978-2-930229-86-7.

  11. Mishra SC, Chhatbar KC, Kashikar A, Mehndiratta A. Diabetic foot. BMJ. 2017; 359: j5064. Published 2017 Nov 16. https://doi.org/10.1136/bmj.j5064.

  12. Armstrong DG, Boulton AJM, Bus SA. Diabetic Foot Ulcers and Their Recurrence. N Engl J Med. 2017; 376 (24): 2367- 2375. doi. 10.1056/NEJMra1615439.

  13. Malhotra R. Shu-Yi Chan C. Nather A. Osteomyelitis in the diabetic foot. Diabetic Foot & Ankle 2014. https://doi. org/10.3402/dfa.v5.24445.

  14. Peters E. Lipsky B. Diagnosis and Management of Infection in the Diabetic Foot. Med Clin N Am 97 (2013) 911-46. https://doi.org/10.1002/9781119445821.ch16.

  15. Senneville E. Nguyen S. Difficult Situations Managing Diabetic Foot. Evidences and Personal Views: Is to Operate on Patients With Diabetic Foot Osteomyelitis Old-Fashioned? Int J Lower Extremity Wounds 2014; 13 (4): 241-46. https:// doi.org/10.1177/1534734614554282.

  16. Islam S, et al. Microbial profile of diabetic foot infections in Trinidad and Tobago. Primary Care Diabetes 2013; 7: 303-8. https://doi.org/10.1016/j.pcd.2013.05.001.

  17. Lima AL, Oliveira PR, Carvalho VC, Cimerman S, et al. Diretrizes Panamericanas para el Tratamiento de las Osteomielitis e Infecciones de Tejidos Blandos Group. Recommendations for the treatment of osteomyelitis. Braz J Infect Dis. 2014; 18 (5): 526-34. https://doi.org/10.1016/j. bjid.2013.12.005.

  18. Jordano Q, Muñiz M, Viadé J, Jaen Á, et al. Osteomielitis de pie diabético: ¿es posible un manejo conservador? Enferm Infecc Microbiol Clin 2014; 32 (9): 555-59. https:// doi.org/10.1016/j.eimc.2014.03.012.

  19. Tone A, Nguyen S, Devemy F, et al. Six-week versus twelveweek antibiotic therapy for non-surgically treated diabetic foot osteomyelitis: a multicenter open-label controlled randomized study [published correction appears in Diabetes Care. Diabetes Care 2015; 38(2): 302-307. https:// doi.org/10.2337/dc14-1514.

  20. García-Ulloa AC, Hernández-Jiménez SC, Ruíz-Gómez DG, Aguilar-Salinas CA. Evaluación del riesgo de amputación en pacientes hospitalizados por pie diabético para validación de una escala pronóstica. Revista de la ALAD 2013; 3: 407-16.

  21. Cisneros-González N, Ascencio-Montiel IJ, Libreros-Bango VN, et al. Índice de amputaciones de extremidades inferiores en pacientes con diabetes [Lower extremity amputation rates in diabetic patients]. Rev Med Inst Mex Seguro Soc 2016; 54 (4): 472-479.

  22. Macías HAE, Álvarez JA, Cabeza VF, et al. Microbiología del pie diabético: ¿es útil el cultivo tomado con hisopo? Gac Med Mex 2011; 147 (2): 117-24.




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Med Int Mex. 2021;37