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2020, Number 2

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Cuba y Salud 2020; 15 (2)

Antimicrobial photodynamic therapy in diabetic foot ulcers

Martínez PS
Full text How to cite this article

Language: Spanish
References: 5
Page: 67-68
PDF size: 236.06 Kb.


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ABSTRACT

Diabetic foot ulcers (UPD) have high morbidity and mortality and high healthcare costs. The healing of these lesions is often delayed by microbial colonization, which can lead to consequences such as amputation. Recent studies propose the use of antimicrobial photodynamic therapy (TFA) in UPDs. This therapy is based on photosensitizing molecules (phenothiazinium, indocyanine green, ethylenediaminetetraacetic acid) that generate reactive oxygen species capable of inducing the destruction of target cells when irradiated with light of an appropriate wavelength, to eradicate pathogenic microorganisms.


REFERENCES

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  2. Perdomo-Celis F, Romero F, Salgado DM, Vega R, Rodríguez J, Angel J, et al. Identification and Characterization at the Single-Cell Level of Cytokine-Producing Circulating Cells in Children With Dengue. J Infect Dis. 2018; 217(9):1472-80.

  3. World Health Organization, Special Programme for Research and Training in Tropical Diseases. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control: New Edition. WHO: Geneva; 2009. Disponible en: https://apps.who.int/iris/bitstream/handle/ 10665/44188/9789241547871_eng.pdf;jsessionid=79F41776AED688B322813DBD0A37024B?sequence=1.

  4. Surmamo WH, Talogo W, Asrin A, Isnuhandojo B, Sahudi A. Failure of hydrocortisone to affect outcome in dengue shock syndrome. Pedia trics. 1982;69:45-49.

  5. Organización Mundial de la Salud. Dengue y dengue grave. 2019. Disponible en: https://www.who.int/es




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Cuba y Salud. 2020;15