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2020, Number 3

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Cuba y Salud 2020; 15 (3)

Epidemic and clinical characterization of COVID-19 patients from Gibara, Holguin, April, 2020

Hernández PA, Escalona AJR, Tamayo PD, Hernández MD, Hernández PEM

Language: Spanish
References: 23
Page: 58-63
PDF size: 837.53 Kb.


ABSTRACT

Objective: to characterize the epidemic and clinical behavior in patients suffering from COVID-19 in Gibara, Holguín, in April 2020.
Materials and methods: a research of series of cases was carried out to characterize the behavior of the COVID-19 in patients of the municipality of Gibara, Holguín from April 1st to the 30th, 2020. The universe was all the confirmed cases with SARS-CoV2 virus. The data were taken from the statistical reports of the Municipal Unit of Hygiene and Epidemiology, and from the survey applied to all the patients.
Results: the study included 30 patients, 28 cases presented a stable clinical evolution and there was a deceased, for a lethal rate of 3,33%; there were 14 asymptomatic patients, which represents 46,66%. The most frequent symptoms were: cough and fever in 11 cases, 36.66%; 26 patients were autochthonous contacts of positive cases (86,67%). The local neighborhoods from the city center had 80% of the cases and a rate of 31.15 X 105.
Conclusions: the COVID-19 in Gibara had more influence in the males, and the most affected age group was from 19 to 40. More than three quarter of the patient are already recovered, more than half were asymptomatic, the cough was the most common symptom and the local neighborhhoods of the city had more than three quarters of the cases.


REFERENCES

  1. Li JY, You Z, Wang Q, Zhou ZJ, Qiu Y, Luo R, Ge XY. The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future. Microbes and Infection [Internet] 2020 [citado 16 mayo 2020]. Disponible en: https://doi. org/10.1016/j.micinf.2020.02.002

  2. World Health Organization. Coronavirus disease (COVID-19) outbreak. Ginebra: WHO; 2020 [15 marzo 2020; citado 16 mayo 2020]. Disponible en: https://www.who.int/emergencies/diseases/novel-coronavirus-2019

  3. Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory síndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents [Internet]. 2020 [citado 16 mayo 2020]; 105924. Disponible en: DOI: 10.1016/j.ijantimicag.2020.105924.

  4. Li F, Li W, Farzan M, Harrison SC. Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science. 2005; 309(5742): 1864-8.

  5. Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun [Internet]. 2020 [citado 6 mayo 2020]; 102433. Disponible en: https://doi.org/10.1016/j.jaut.2020.102433.

  6. Sohrabi C, Alsafi Z, O’Neill N, Khan M, Kerwan A, Al-Jabir A et al. World Health Organization declares Global Emergency: A review of the 2019 Novel Coronavirus (COVID-19). Int J Surg [Internet]. 2020 [citado 6 mayo 2020]; S1743-9191(20). Disponible en: https://doi. org/10.1016/j.ijsu.2020.02.034.

  7. Cui J, Li F, Shi Z-L. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol. 2019;17(3):181-92.

  8. Sun P, Lu X, Xu C, Sun W, Pan B. Understanding of COVID-19 based on current evidence. J Med Virol [Internet]. 2020 [citado 6 mayo 2020]. Disponible en: https://doi.org/10.1002/jmv. 25722.

  9. Chen Y, Liu Q, Guo D. Coronaviruses: genome structure, replication, and pathogenesis. J Med Virol [Internet]. 2020 [citado 6 mayo 2020]. Disponible en: https://doi.org/10.1002/jmv.25681.

  10. Han Q, Lin Q, Jin S, You L. Recent insights into 2019-nCoV: a brief but comprehensive review. J Infect [Internet]. 2020 [citado 6 mayo 2020]; 4453(20). Disponible en: https://doi.org/10.1016/j.jinf.2020.02.010.

  11. Minsap. Nota informativa sobre la COVID-19 en Cuba [Internet]. La Habana: Editorial de ciencias médicas; 2020. [1 de mayo 2020; citado 6 mayo 2020]. Disponible en: https://temas.sld.cu/coronavirus/category/actualidades/nota-informativa-del-minsap/

  12. Kim Y-I, Kim S-G, Kim S-M, Kim E-H, Park S-J, Yu K-M, et al. Infection and Rapid Transmission of SARS-CoV-2 in Ferrets. Cell Host Microbe [Internet]. 2020 [citado 6 mayo 2020]; Disponible en: http://www.sciencedirect.com/ science/ article/ pii/ S 1931312820301876

  13. Hung LS. The SARS epidemic in Hong Kong: what lessons have we learned? J R Soc Med [Internet]. agosto de 2003 [citado 6 mayo 2020];96(8):374-8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539564/

  14. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med [Internet]. 28 de febrero de 2020 [citado 6 mayo 2020]; Disponible en: https://www.nejm.org/ doi/10. 1056 /NEJM oa 2002032

  15. European Center for Disease Control and Prevention. Coronavirus disease 2019 (COVID-19) pandemic: increased transmission in the EU/EEA and the UK – seventh update [Internet].;2020. [citado 6 mayo 2020]; Disponible en: https://www. ecdc. europa.eu/sites/default/ files/documents/RRA-seventh-update-Outbreak-of-coronavirus-disease-COVID-19.pdf

  16. Russell CD, Millar JE, Baillie JK. Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury. Lancet [Internet]. 2020. [citado 6 mayo 2020]; Disponible en: DOI: S0140-6736(20)30317-2 [pii].

  17. World Health Organization. Coronavirus disease (COVID-19) outbreak. Ginebra: WHO [Internet]. 2020 [citado 6 mayo 2020]. Disponible en: https://www.who.int/emergencies/diseases/novel-coronavirus-2019

  18. Centers for Disease Control and Prevention. Interim Infection Prevention and Control Recommendations for Patients with Known or Patients Under Investigation for 2019 Novel Coronavirus (2019-nCoV) in a Healthcare Setting: CDC [Internet]. 2020 [citado 6 mayo 2020]. Disponible en: https://www.cdc.gov/coronavirus/2019-nCoV / hcp/infection-control.html

  19. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet Lond Engl. 30 de enero de 2020; https://www.thelancet.com/journals/lancet/ article/PIIS0140-6736(20)30211-7/fulltext

  20. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med [Internet]. 28 de febrero de 2020 [citado 6 de marzo de 2020]; Disponible en: https://www.nejm.org/doi/10.1056/NEJMoa2002032

  21. Wang J, Tang K, Feng K, Lv W. High Temperature and High Humidity Reduce the Transmission of COVID-19 [Internet]. Rochester, NY: Social Science Research Network; 2020 mar [citado 6 de mayo de 2020]. Disponible en: https://papers.ssrn.com/abstract=3551767

  22. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. Vital Surveillances: The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19). China CDC Wkly [Internet]. 2020 febrero [citado 6 de mayo de 2020]. Disponible en: http://weekly.chinacdc.cn/ en/article/id/ e53946e2-c6c4-41e9-9a9b-fea8db1a8f51

  23. Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med [Internet]. 24 de febrero de 2020 [citado 6 de mayo de 2020]. Disponible en: https://www.thelancet.com/ journals / lanres/ article/PIIS2213-2600(20)30079-5/abstract




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