medigraphic.com
SPANISH

Panorama Cuba y Salud

  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 3

<< Back Next >>

Cuba y Salud 2020; 15 (3)

COVID-19: medication risks without evidence

Lovo J
Full text How to cite this article

Language: Spanish
References: 25
Page: 98-103
PDF size: 274.81 Kb.


Key words:

bioethics, bioethical issues, patient rights, coronavirus Infections.

ABSTRACT

Introduction: the appearance of global health crises, such as that generated by the SARS Cov-2 virus, generate profound ethical dilemmas. The population demands measures of attention and prophylaxis quickly. Encouraging that many people, including health professionals, offer medications without any evidence.
Objective: to argue the need for evidence, in the medications offered for the management and prevention of COVID-19.
Development: Evidence-based medicine appears as such after the 1900s. Before this date, medicine was based on belief and experience. With the emergence of the current health crisis, the population is demanding medications to cure the disease. This allows people to appear, offering unproved treatments and promoting no evidence prophylaxis drugs.
Conclusions: there is no drug specifically approved for the treatment or prophylaxis of COVID-19. All interventions must be established on the principles of medicine based on the best available evidence.


REFERENCES

  1. Ahn DG, Shin HJ, Kim MH et al. Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). J Microbiol Biotechnol [Internet]. 2020;30(3):313-24. [citado 01/06/2020]. Disponible en: https://doi.org/10.4014/jmb.2003.03011

  2. Contini C, Di Nuzzo M, Barp N et al. The novel zoonotic COVID-19 pandemic: An expected global health concern. J Infect Dev Ctries [Internet]. 2020;14(3):254-64. [citado 01/06/2020]. Disponible en: https://doi.org/10.3855/jidc.12671

  3. Giubilini A, Douglas T, Maslen H, Savulescu J. Quarantine, isolation and the duty of easy rescue in public health. Dev World Bioeth[Internet]. 2018;18(2):182-89. [citado 01/06/2020]. Disponible en: https://doi.org/10.1111/dewb.12165

  4. Bryant KB. We Can’t Just Wash Our Hands: a Primary Care Physician’s Thoughts on COVID-19 and Her Community [published online ahead of print, 2020 Apr 20]. J Gen Intern Med [Internet]. 2020;1-2. [citado 01/06/2020]. Disponible en: https://doi.org/10.1007/s11606-020-05831-0

  5. Erku DA, Belachew SA, Abrha S, et al. When fear and misinformation go viral: Pharmacists’ role in deterring medication misinformation during the ‘infodemic’ surrounding COVID-19 [published online ahead of print, 2020 May 1]. Res Social Adm Pharm [Internet]. 2020;S1551 (20). [citado 02/06/2020]. Disponible en: https://doi.org/10.1016/j.sapharm.2020.04.032

  6. Sesagiri Raamkumar A, Tan SG, Wee HL. Measuring the Outreach Efforts of Public Health Authorities and the Public Response on Facebook During the COVID-19 Pandemic in Early 2020: Cross-Country Comparison. J Med Internet Res[Internet]. 2020;22(5):e19334. [citado 02/06/2020]. Disponible en: https://doi.org/10.2196/19334

  7. Tonelli MR. Evidence-free medicine: forgoing evidence in clinical decision making. Perspect Biol Med [Internet]. 2009;52(2):319-31. [citado 02/06/2020]. Disponible en: https://doi.org/10.1353/pbm.0.0087

  8. Black D. Evidence-free medicine. Clin Med (Lond) [Internet]. 2002;2(5):474-75. [citado 02/06/2020]. Disponible en: https://doi.org/10.7861/ clinmedicine.2-5-474

  9. Sackett DL, Rosenberg WMC, Gray JAM, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn’t. BMJ[Internet]. 1996; 312(7023), 71–2. [citado 02/06/2020]. Disponible en: https://doi.org/10.1136/bmj.312.7023.71

  10. Tonelli MR, Shapiro D. Experiential knowledge in clinical medicine: use and justification [published online ahead of print, 2020 Apr 24]. Theor Med Bioeth [Internet] . 2020. [citado 03/06/2020]. Disponible en: https://doi.org/10.1007/s11017-020-09521-0

  11. Djulbegovic B, Guyatt GH. Progress in evidence-based medicine: a quarter century on. Lancet[Internet]. 2017;390(10092):415-23. [citado 03/06/2020]. Disponible en: https://doi.org/10.1016/S0140-6736(16)31592-6

  12. Tonelli MR. The challenge of evidence in clinical medicine. J Eval Clin Prac[Internet] . 2010; 16(2), 384-89. [citado 04/06/2020]. Disponible en: https://doi.org/10.1111/j.1365-2753.2010.01405.x

  13. Vellingiri B, Jayaramayya K, Iyer M, Narayanasamy A, Govindasamy V, Giridharan, B et al. COVID-19: A promising cure for the global panic. Sci Total Environ [Internet]. 2020;725. [citado 04/06/2020]. Disponible en: https://doi.org/10.1016/j.scitotenv.2020.138277

  14. Broche Candó JM, Broche Candó RC, García Hernández LY, Cañedo Andalia R. Medicina basada en la evidencia: un reto para el médico contemporáneo. ACIMED [Internet]. 2003; 11( 6 ). [citado 04/06/2020]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_ arttext&pid=S1024-94352003000600003&lng=es.

  15. Manzini JL. declaración de helsinki: principios éticos para la investigación médica sobre sujetos humanos. Acta bioeth [Internet]. 2000 ; 6( 2 ): 321-34. [citado 05/06/2020]. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S1726-569X2000000200010&lng=es

  16. Krouse HJ. Whatever Happened to Evidence-Based Practice During COVID-19? [published online ahead of print, 2020 May 19]. Otolaryngol Head Neck Surg[Internet]. 2020. [citado 05/06/2020]. Disponible en: https://doi.org/10.1177/0194599820930239

  17. Wu J, Zha P. Flaws In Medicine Must Be Corrected: An Open Report to National Governments amid the Pandemic [e-book].1er ed. Healthtier World[Internet]. 2020. [citado 07/06/2020]. Disponible en: https://doi.org/10.31219/osf.io/6wy9j

  18. Lenzer J, Brownlee s. Pandemic Science Out of Control. Issues in Science and Technology [Internet]. 2020, abril 28. [citado 07/06/2020]. Disponible en: https://issues.org/pandemic-science-out-of-control/

  19. Smith CM. Origin and uses of primum non nocere--above all, do no harm!. J Clin Pharmacol [Internet]. 2005;45(4):371-77. [citado 07/06/2020]. Disponible en: https://doi.org/10.1177/0091270004273680

  20. Centers for Disease Control and Prevention. Information for clinicians on investigational therapeutics for patients with COVID-19. [citado 08/06/2020]. Disponible en: https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic-options.html

  21. Oliva Marín J. Posibles estrategias de tratamiento para COVID-19. [published online ahead of print]. Alerta [Internet]. 6may 2020 ;3(2). [citado 08/06/2020]. Disponible en: https://doi.org/10.5377/alerta.v3i2.9626

  22. Soto A. Cuando la vehemencia supera la evidencia: el caso del uso de hidroxicloroquina para el tratamiento del COVID-19. Acta méd. Peru [Internet]. 2020 ; 37( 1 ): 110-11. [citado 09/05/2020]. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1728- 59172020000100110&lng=es. http://dx.doi.org/10.35663/amp.2020.371.914

  23. Agrawal S, Goel AD, Gupta N. Emerging prophylaxis strategies against COVID-19. Monaldi Arch Chest Dis [Internet].2020; 90(1):169-72. [citado 09/06/2020]. Disponible en: http://dx.doi.org/10.4081/monaldi.2020.1289

  24. Chary MA, Barbuto AF, Izadmehr S, Hayes BD, Burns MM. COVID-19: Therapeutics and Their Toxicities [published online ahead of print, 2020 Apr 30]. J Med Toxicol[Internet] . 2020;1-11. [citado 10/06/2020]. Disponible en: http://dx.doi.org/10.1007/s13181-020-00777-5

  25. Pascarella G, Strumia A, Piliego C, et al. COVID-19 diagnosis and management: a comprehensive review [published online ahead of print, 2020 Apr 29]. J Intern Med [Internet]. 2020; 00: 1-15. [citado 11/06/2020]. Disponible en: http://dx.doi.org/10.1111/joim.13091




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Cuba y Salud. 2020;15