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>Journals >Medicina Crítica >Year 2007, Issue 1


Laue NML, Risco CRE, López AMA, Galicia TJ
Development of a pediatric multiple organ dysfunction outcome score (EPPDOM).
Rev Asoc Mex Med Crit y Ter Int 2007; 21 (1)

Language: Español
References: 23
Page: 31-37
PDF: 69.35 Kb.


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ABSTRACT

Introduction: The multiorganic dysfunction is frequently observed in critical care and his mortality is high.
Objective: To design a score for the evaluation of the multiple organ dysfunction in children.
Material and methods: Prospective cohort study, consist in the search of organic failure in patients which interned in the service, selection of variables and construction of 4 models applicable in the initial, days 3, 5 and critic.
Statistic tests: Relative risk of dead, t of Student, Mantel-Haenszel, Wilcoxon and Logistic regression.
Results: 559 patients evaluated, 171 with multiorganic dysfunction. The EPPDOM models predict mortality in 73-76% in the 4 moments of evaluation. The association of failures cardiovascular-respiratory-renal was observed in 60% of the patients which die, with rr = 1.6. The sequential evaluation showed what in 81% of patients the 4 predictions was accurate or exist only one error.
Discussion and conclusions: The intestine, the sepsis and the two-hits are important in the pathogenesis of the multiple organ dysfunction syndrome, nevertheless the majority of the scores not evaluate this conditions.
Conclusions: The EPPDOM score satisfactory predict mortality and survive in 4 important moments of the evaluation of this disease, value 7 organic systems and include epidemiological variables.


Key words: Multiorganic failure, prognostic score, children.


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>Journals >Medicina Crítica >Year 2007, Issue 1
 

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