Revista de Hematología

Contents by Year, Volume and Issue

Table of Contents

General Information

Instructions for Authors

Message to Editor

Editorial Board

>Journals >Revista de Hematología >Year 2013, Issue 1

Ramos-Peñafiel CO, Martínez-Tovar A, Olarte-Carrillo I, Collazo-Jaloma J
Our war against cancer: A Darwinian approach
Rev Hematol Mex 2013; 14 (1)

Language: Español
References: 25
Page: 47-50
PDF: 557.04 Kb.

Full text


Cancer is one of the leading causes of death around the world. The number of cases continues to increase especially in certain groups such as pediatric patients. The state of the art of treatment is chemotherapy on the basis of kill the tumor cell. This strategy has failed despite the addition of strategies as inhibitors of tyrosine kinase or immunotherapy. One of the theories that have marked the development of humanity is the evolution of species. Evolution means development, progress and differentiation, situation that also fulfills all the cells including tumor cells. Darwinism is a current which can helps us to understand the success of the tumor cells over the other cells.

Key words: Cancer, Darwinism, Pansperm.


  1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008. GLOBOCAN 2008. Int J Cancer 2010;127: 2893-2917.

  2. Tirado-Gómez L, Mohar-Betancourt A. Epidemiología de las Neoplasias Hemato-Oncológicas. Cancerología 2007;2:109- 120.

  3. Pérez-Saldivar ML, Fajardo-Gutiérrez A, Bernáldez-Ríos R, Martínez-Avalos A, Medina-Sanson A, Espinosa-Hernández L, et al. Childhood acute leukemias are frequent in Mexico City: descriptive epidemiology. BMC Cancer 2011;11:355.

  4. Mejía-Aranguré JM, Fajardo-Gutiérrez A, Bernáldez-Ríos R, Paredes-Aguilera R, Flores-Aguilar H, Martínez-García MC. Incidence of acute leukemia in children in Mexico City, from 1982 to 1991. Salud Pública Mex 2000;42:431-437.

  5. González-Salas WM, Olarte-Carrillo I, Gutiérrez-Romero M, Montaño-Figueroa EH, Martínez-Murillo C, Ramos-Peñafiel CO. Acute leukemia frequency observed in a reference hospital. Rev Med Inst Mex Seguro Soc 2012;50:167-171.

  6. Ferdinand R, Mitchell SA, Batson S, Tumur I. Treatments for chronic myeloid leukemia: a qualitative systemic review. J Blood Med 2012;3:51-76.

  7. Erren TC, Groß JV, Koch MS, Erren M, Meyer-Rochow VB. What Do We Know 40 Years After Nixon Declared the ‘War on Cancer’? On the Origin, Prevention and Treatment of Cancer. DOI 10.1007/s13187-012-0411-7

  8. Puroshotham A, Sullivan R. Darwin, medicine and cancer. Ann of Oncol 2010;21:199-203.

  9. Kuzawa C. Why evolution needs development and medicine needs evolution. Int J Epidemiol 2012;41:223-229.

  10. Liu Y, Li X. Darwin´s Pangenesis and molecular medicine. Trends Mol Med 2012;18: 506-508.

  11. Osman A. MicroRNAs in health and disease-basic science and clinical applications. Clin Lab 2012;58:393-402.

  12. Kandouz M. The Eph/Ephrin family in cancer metastasis: communication at the service of invasion. Cancer Metastasis Rev 2012;31:353-373.

  13. Huxley J. Evolution The Modern Synthesis (Allen&Urwin, London, 1942).

  14. Greaves M. Cancer: the evolutionary legacy. Oxford University Press, 2001.

  15. Khare S, Verma M. Epigenetics of colon cancer. Methods Mol Biol 2012;863:177-185.

  16. Mitrus I, Bryndza E, Sochanik A, Szala S. Evolving models of tumor origin and progression. Tumour Biol 2012;33:911-917.

  17. Martinelli G, Lacobucci I, Papayannidis C, Soverini S. New targets for Ph+ leukaemia therapy. Best Pract Res Clin Haematol 2009;22:445-454.

  18. Cornell RF, Palmer J. Adult acute leukemia. Dis Mon 2012;58:219-238.

  19. Merlo L, Pepper J, Reid B, Maley C. Cancer as an evolutionary and ecological process. Nat Rev Cancer 2006;6(12):924-935.

  20. Little MP. Cancer models, genomic instability and somatic cellular Darwinian evolution. Biol Direct 2010;5:19.

  21. Bombonati A, Sgroi DC. The molecular pathology of breast cancer progression. J Pathol 2011;223:307-317.

  22. Vineis P, Matullo G, Manuguerra M. An evolutionary paradigm for carcinogenesis? J Epidemiol Community Health 2003;57:89-95.

  23. Hiwarkar P, Rao A. Revisiting Darwinism explains extinction of fetal erythroid progenitors in a leukaemogenic model of a paediatric myeloproliferative neoplasm. BJH 2011;155:2.

  24. Sugimoto T. Darwinian evolution does not rule out the gaia hypothesis. J Theor Biol 2002;21:447-455.

  25. Bard J. The next evolutionary synthesis: from Lamarck and Darwin to genomic variation and systems biology. Cell Commun Signal 2011;9:30.

>Journals >Revista de Hematología >Year 2013, Issue 1

· Journal Index 
· Links 

Copyright 2019