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>Journals >Revista Médica del Instituto Mexicano del Seguro Social >Year 2009, Issue 1

Hernández-Valencia M, Zárate A
Endometriosis. Pathophysiological Background for Treatment
Rev Med Inst Mex Seguro Soc 2009; 47 (1)

Language: Español
References: 34
Page: 57-60
PDF: 31.60 Kb.

Full text


Endometriosis is the third cause of gynecological morbidity and the complications are associated to ectopically endometrial tissue implantation. The interest on this disease is the functional disability and its association with sterility. It has been established that endometrial growth is estrogen-dependent and that progesterone inhibits the cellular proliferation mediated by estrogens, therefore in endometriosis there is not an adequate response to hormonal signals that control the proliferative activity. It has been described that peritoneal fluid in women with endometriosis has high cytokines concentrations, growth factors and activated macrophages, which had shown adverse effects on fertility. Therefore, these are not the only causes of infertility since it has been described that endometriosis seems to have poor ovarian reserve and ovular quality. When there is infertility, the tendency is to treat the endometriosis due to the changes caused by ectopically tissue presented at immunological level and in the structure of genital organs, which disturbances the conception process. It has been observed that endometriosis has recurrences after a surgical procedure. For this reason we should be consider all therapeutic possibilities.

Key words: endometriosis, infertility, aromatase.


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>Journals >Revista Médica del Instituto Mexicano del Seguro Social >Year 2009, Issue 1

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