Entrar/Registro  
HOME SPANISH
 
Revista Médica del Instituto Mexicano del Seguro Social
   
MENU

Contents by Year, Volume and Issue

Table of Contents

General Information

Instructions for Authors

Message to Editor

Editorial Board






>Journals >Revista Médica del Instituto Mexicano del Seguro Social >Year 2006, Issue 3


Tamez-Pérez HE, Sáenz-Gallegos R, Hernández-Rodríguez K, Forsbach-Sánchez G, Gómez-de Ossio MD, Fernández-Garza N, Zapata-de la Garza E, Tamez-Peña AL
Insulin Therapy in Patients with Severe Hypertriglyceridemia
Rev Med Inst Mex Seguro Soc 2006; 44 (3)

Language: Español
References: 12
Page: 235-237
PDF: 72.85 Kb.


Full text




ABSTRACT

A series of seven patients with severe hypertrigly-ceridemia (triglyceride levels › 1000 mg/dL) is presented. Four of the patients were diabetics, two of them were in treatment with anti-retroviral drugs, and three of them presented acute pancreatitis. In all patients intravenous infusion of insulin was initiated at a rate of 0.05-2 U/kg/day. Two and a half days after this treatment, the serum triglyceride level remained lower than 400 mg/dL. There were no complications during the treatment. The long treatment included basal insulin, fibrates and avoidance of pharmacotherapy. Insulin therapy for diabetic and non-diabetic patients with severe hypertrigly-ceridemia is an effective and safe treatment.


Key words: hypertriglyceridemia, pancreatitis, insulin therapy.


REFERENCIAS

  1. 1. Kahn R, Buse J, Ferranini E, Stern M. The meta-bolic syndrome: time for a critical appraisal. Diabetes Care 2005;28:2289-2304.

  2. 2. Dumbar RL, Rader DJ. Demistifying triglycerides: a practical approach for the clinician. Cleve Clin J Med 2005;8:661-680.

  3. 3. Broede UC, Rader DJ. Gene therapy for lipo-protein disorders. Expert Opin Biol Ther 2005;8: 1029-1038.

  4. 4. Jabbar M, Zuhri-Yafi M, Larrea J. Insulin therapy for non diabetic patient with severe hypertriglyceri-demia. J Am Coll Nutr 1999;17:458-461.

  5. 5. Mkhail N, Triverdi K, Page C, Wali S, Cope D. Treatment of severe hypertriglyceridemia in non diabetic patients with insulin. Am J Emerg Med 2005;23:415-417.

  6. 6. Tamez-Pérez HE, Gómez-de Ossio MD, Tamez-Peña AL. Lipotoxicidad en la diabetes mellitus tipo 2. Med Interna Mex 2004;20:341-346.

  7. 7. Isley W. Tough hipertrigliceridemia cases. Endocrine Society 87, Annual Meeting 2005. p. 173-178.

  8. 8. Green ML. Evaluation and management of dislipi-demia in patients with HIV infection. J Gen Intern Med 2002;17:797-810.

  9. 9. Loh JA, Rickels MR, Williams J. Total parenteral nutrition in management of hyperlipidemic pan-creatitis during pregnancy. Endocr Pract 2005; 11:325-330.

  10. Jonker J, Mohrschladt M, Westendorp R, Laarse A, Smelt A. Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: reversal bezafibrate therapy in a randomized con-trolled trial. Am J Med 2002;112:275-280.

  11. Krinsley JS. Effect of an intensive glucose manage-ment protocol on the mortality of critically ill adult patients. Mayo Clin Proc 2004;9:992-1000.

  12. Levetan CS. Effect of hyperglycemia on stroke outcomes. Endocr Pract 2004;10(Suppl 2):34-39.






>Journals >Revista Médica del Instituto Mexicano del Seguro Social >Year 2006, Issue 3
 

· Journal Index 
· Links 






       
Copyright 2019