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>Journals >Medicina Cutánea Ibero-Latino-Americana >Year 2013, Issue 1


Camacho FM, Camacho-Serrano F, Moreno GJC, García HMJ, Polo PJ, Perea CM, Coronel MI
Treatment of alopecias of male and female patterns. Clinical efficacy of aminexil and SP94 in two surveys of 180 patients, men and women
Med Cutan Iber Lat Am 2013; 41 (1)

Language: Español
References: 18
Page: 18-33
PDF: 200.79 Kb.


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ABSTRACT

Effect of aminexil combined with SP94 was evaluated as positive in a group of patients of both genders. To confirm these positive effects a survey in 180 patients of each gender has been performed in two Trichology Units of two Hospitals. Patients applied 6 ml. of the lotion in humid scalp all the nights. Controls to the start of treatment and at 45, 90, and 180 days was realized. Graduation of alopecia in accordance with the Ebling’s and Ludwig’s scales, and diferentiation on four group of age (less than 17 year, between 18 and 34 years, between 35 and 49 years, and more than 50 year) was performed. All the patients were asked about their clinical background or treatments realized, seborrhoeic dermatitis, number of hairs shedding in a wash 48 hour before, nutritional deficiencies or congenital errors. Women with clinical signs of SAHA syndrome an hormonal analysis was performed.
Exploration of patients at each visit included trichogram and study of the hair diameter, pull sign, sebometry, corneometry, photographic control, graduation of alopecia, and a valoration of seborrhoeic dermatitis evolution in a quantitative scale. In each visit was also asked to patients for a evaluation about cosmeticity and efficacy of the lotion, by which of a subjecitive manner was divided in worst, similar, acceptable-better, and excellent, that was contrasted with the opinion of two physicians that had their evaluation based on the signs and photograph of each visit. Patient’s compliment was study with the Morisky-Green’s questionnaire. Patients that do not follow the protocol of application or that did not attend to some visit were substituted. Results permit to assure aminexil associated with SP.94 stop or delay loss of hair and favored its wide, although regroth of new hair lost in the evolutive process of androgenetic alopecia was not demonstrated, neither its actuation in seborrhorea and soborrhoeic dermatitis.


Key words: Aminexil, SP94, alopecia, efficacy.


REFERENCIAS

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  2. Camacho F, Tosti A. Tratamiento médico de las alopecias femeninas. Monogr Dermatol 2005; 18: 92-117.

  3. Camacho F, Montagna W. Alopecia androgenética masculina. En: Camacho F, Montagna W, eds. Tricología. Aula Médica Ed., Madrid, 1996; 325-42.

  4. Zappacosta AR. Reversal of baldness in patient recei-ving minoxidil for hypertension. N Engl J Med 1980; 303: 1480-1.

  5. Lachgar S, Chaveron M, Gali Y, Bonafe JL. Minoxidil upregulates the expression of vascular endotelial growth factor in human hair dermal papilla cells. Br J Dermatol 1998; 138: 407-11.

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  7. Bernard B. De los avances en fisiopatología del cabello a la nueva visión en el tratamiento global de la alopecia. Med Cutan Iber Lat Amer 2009; 37: 111-3.

  8. Bouloc A. Tratamientos cosméticos en alopecia: el SP94, una molécula 2 en 1: un agente doble para el folículo piloso. Med Cutan Iber Lat Amer 2008; 36: 104-7.

  9. Gayoso MJ, Camacho F, Díaz-Flores L, Dulanto F, Montagna W. Aspectos anatomofisiológicos de interes em Tricología. En Camacho F, Montagna W, eds. Tricología. Trichology. Trichologie. EGRAF Ed, Madrid, 1981; 39-69.

  10. Camacho F, Montagna W. Metabolismo del folículo piloso. Investigación: genética e inmunología. En: Camacho M, Montagna W, eds. Tricología. Enfermedades del folículo pilosebáceo. Madrid: Aula Médica Ed, 1996; 75-96.

  11. Vingler P, Gautier B, Dalko M, Rozot R, Gaillard O, Michelet JF, Bernard BA. 6-O glucose linoleate supports in vitro human hair growth and lipid synthesis. Int J Cosmet Sci 2007; 29: 1-11.

  12. Camacho FM, Coronel MI. Tratamiento cosmético de las alopecias no inmunológicas. Eficacia clínica del Aminexil SP94. Med Cutan Iber Lat Amer 2008; 36: 96-103.

  13. Camacho FM, Rodríguez Rey EM. Alopecias de patrón femenino en la adolescencia y mujer premenopáusica. Monogr Dermatol 2007; 20: 261-92.

  14. Camacho F, Montagna W. Alopecias por miniaturización folicular. Alopecias androgenéticas. Historia de las clasificaciones. Monogr Dermatol 2005; 18: 3-16.

  15. Camacho F, Montagna W. Alopecia androgenética masculina. Monogr Dermatol 2005; 18: 36-53.

  16. Camacho FM. Hair loss in women. Sem Cutan Med Surg 2009; 28: 19-32.

  17. Serrano Ortega S, Serrano Falcón C. Exploración del cuero cabelludo. Pitiriasis y seborrea. Monogr Dermatol 2009 (Num. Extra); 22: 10-6.

  18. Mascaró Galy JM. Afecciones eritematoescamosas del cuero cabelludo del adulto: dermatitis seborreica y síntomas acompañantes. Monogr Dermatol 2009 (Num. Extra); 22: 22-9.






>Journals >Medicina Cutánea Ibero-Latino-Americana >Year 2013, Issue 1
 

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