Ginecología y Obstetricia de México

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>Journals >Ginecología y Obstetricia de México >Year 2019, Issue 09

Villalobos-Equihua C, Ruiz-Marines D, Ortíz-Verdín MD, Martínez-Hernández FJ
Ewing's sarcoma as a cause of abnormal uterine bleeding. Report of a case
Ginecol Obstet Mex 2019; 87 (09)

Language: Español
References: 6
Page: 610-614
PDF: 284.88 Kb.

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Background: Primitive neuroectodermal tumors originate from mesenchymal progenitor cells and are part of various neoplasms, known as the Ewing family tumors. Its expression in the female reproductive system (mainly in the ovary and the uterine body) is an exceptional event.
Clinical case: A 13-year-old patient, who went to the Gynecological Emergency Department of the Hospital de la Mujer de Morelia, Michoacán, with hypermenorrhea of 5 months of evolution, colic pain in the hypogastrium, without improvement despite the use of analgesics; loss of 3 kg in 1 month and affectation to the general state of health. A physical examination was found: abdomen with a tumor of 10 x 10 cm in the pelvic hollow. It was decided to perform exploratory laparotomy with total abdominal hysterectomy, right oophorectomy and left salpingectomy. The pathology study reported a small round and blue cell tumor that affected the bottom of the vaginal sac and cervix. The immunohistochemical study confirmed the diagnosis of Ewing's sarcoma. The patient was sent to the Oncology state center to receive chemotherapy and radiotherapy; however, it was lost in the follow-up.
Conclusions: Abnormal uterine bleeding is one of the most frequent reasons for gynecological consultation in adolescents, which associated with some neoplasm is an exceptional event. Ewing sarcomas constitute less than 1% of malignant lesions of the cervix. Despite its low prevalence and few cases reported in the literature, it should be considered in the differential diagnosis of gynecological tumors.

Key words: Primitive neuroectodermal tumor, Mesenchymal progenitor cells, Hypermenorrhea, Ewing sarcoma, Adolescents.


  1. Elizalde CR, et al. Primitive neuroectodermal tumor of the uterus. Gynecol Oncol Rep 2016;18:25-28. DOI: 10.1016/j. gore.2016.07.001

  2. Malpica A. Miscellaneous cervical neoplasm. In: Muter G, et al. Pathology of the female reproductive tract. 3rd ed. 2014;275-289.

  3. Vivas-Flores CI, et al. Sarcoma de Ewing extraóseo de origen ginecológico: tumor neuroectodérmico primitivo de localización infrecuente. Reporte de caso y revisión de la literatura. Rev Colombiana Obstet Ginecol 2017;68(2):135-141. DOI: https://doi.org/10.18597/ rcog.3023

  4. Nazia Mashriqi, et al. Ewing´s sarcoma of the cervix, a diagnostic dilemma: a case report and review of the literature. J Med Case Rep 2015;9:255. doi: 10.1186/ s13256-015-0733-2

  5. McCluggage WG. Practical biomarkers for female genital tract lesions. In: Muter G, et al. Pathology of the female reproductive tract. 3rd ed. 2014;828-845.

  6. Yousefi Z, et al. Peripheral primitive neuroectodermal tumor of the pelvis. Iran J Medi Sci 2014;39:71- 7 4 . https://pdfs.semanticschol .org/7a10/c38972b5b221244984066e73bc9c8b563ba8. pdf?_ga=2.255821135.638661514.1566345520- 2048599257.1560991831

>Journals >Ginecología y Obstetricia de México >Year 2019, Issue 09

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