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Federación Mexicana de Ginecología y Obstetricia, A.C.

2022, Número 05

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Ginecol Obstet Mex 2022; 90 (05)


Relación entre hierro y diabetes mellitus gestacional: una revisión narrativa

Márquez-Ibarra AA, Mariscal-Ramírez BE, González-Ponce AM, Valbuena-Gregorio E

Idioma: Español
Referencias bibliográficas: 34
Paginas: 434-442
Archivo PDF: 223.34 Kb.


RESUMEN

Objetivo: Evaluar la evidencia científica acerca de la relación entre el hierro y la diabetes mellitus gestacional.
Metodología: Revisión narrativa, fundamentada en la búsqueda de artículos publicados de 2000 a 2021 en las bases de datos de PubMed, LILACS, BIREME, NICE, SIGN y CENETEC con los MeSH: Iron, iron and diabetes, Iron overland, Gestational Diabetes y Iron overland and Gestational Diabetes. Se seleccionaron los relacionados con el tema de interés.
Resultados: Se encontraron 119 artículos y solo 34 se consideraron adecuados para el objetivo de la revisión porque estaban directamente relacionados con el metabolismo del hierro, diabetes gestacional y el hierro como causa de diabetes gestacional. Se obtuvieron estudios transversales, casos y controles, cohortes, ensayos, revisiones y metanálisis.
Conclusiones: La relación entre hierro y diabetes mellitus gestacional no está debidamente establecida; sin embargo, se ha relacionado con la capacidad oxidativa del hierro por diferentes mecanismos que acentúan la resistencia a la insulina. Se sugiere que las concentraciones elevadas de hierro podrían ser un factor de riesgo de diabetes mellitus gestacional.


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