2025, Número 1
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Arch Med Urg Mex 2025; 17 (1)
El primer factor NO se olvida: relevancia del fibrinógeno en el manejo del choque hemorrágico
Ballesteros-Flores CG, Ballesteros-Rentería G, Terán-Flores H, Navarrete-Colin YA
Idioma: Español
Referencias bibliográficas: 30
Paginas: 54-57
Archivo PDF: 177.44 Kb.
RESUMEN
Introducción: El fibrinógeno, también llamado Factor I. Es una
glicoproteina plasmática dimérica con propiedades globulares/fibrosas
y de elevado peso molecular (340 kDa). En adultos sanos, la
concentración plasmática se encuentra en rango de 2 a 4 g/L.
Objetivo:
Análisis bibliográfico sobre los principales aspectos bioquímicos
del fibrinógeno en pacientes con trauma.
Material y Métodos: Revisión
de la literatura médica en idioma ingles durante el periodo 2022
a 2024. Se seleccionaron los artículos científicos más relevantes de
fibrinógeno y trauma.
Resultados: El fibrinógeno, se encuentra disminuido
frecuentemente en pacientes que presentan un estado de
choque hemorrágico. El nivel de fibrinógeno crítico es ≤ 1 g/L. De tal
manera, se recomienda mantener un nivel de fibrinógeno plasmático
≥ 2 g/L.
Conclusión: La presente revisión bibliográfica, demuestra
que los pacientes con estado de choque hemorrágico, tendrán una
disminución significativa del fibrinógeno plasmático.
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