Muñoz-Flores J, Santiago-González S

Idioma: Español
Referencias bibliográficas: 30
Paginas: 79-85
Archivo PDF: 606.25 Kb.

RESUMEN

Introducción: la coledocolitiasis residual se presenta en al menos el 2% de los pacientes posoperados de colecistectomía, con informes de hasta el 5 a 12%. Objetivo: evaluar el valor predictivo de la gamma-glutamil transferasa y fosfatasa alcalina preoperatorias en el diagnóstico de coledocolitiasis residual. Material y métodos: estudio tipo cohorte retrospectiva, (observacional, transversal, analítico y retrospectivo), con 178 pacientes, mayores de 18 años, que fueron sometidos a colecistectomía. El análisis estadístico fue de tipo descriptivo e inferencial (regresión logística, curvas ROC, índice de Youden). Resultados: la edad media fue de 43.85 años. El 3.93% (n = 7) de los pacientes presentaron coledocolitiasis residual. Los puntos de corte, 91.5 UI/l para gamma-glutamil transferasa y 106 UI/l para fosfatasa alcalina, mostraron alta sensibilidad (100 y 85.7%, respectivamente) y especificidad (94.2 y 75.4%, respectivamente). Conclusiones: los niveles preoperatorios de gamma-glutamil transferasa y fosfatasa alcalina están asociados con coledocolitiasis asintomática. Estas enzimas podrían ayudar a identificar a los pacientes que deben ser sometidos a colangiografía transoperatoria.

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