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2026, Número S1

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Rev Mex Anest 2026; 49 (S1)


Anestesia del paciente gran quemado en estado hipermetabólico

Rodríguez-Delgado, GM

Idioma: Español
Referencias bibliográficas: 36
Paginas: 420-423
Archivo PDF: 812.15 Kb.


FRAGMENTO

INTRODUCCIÓN

El estado hipermetabólico posterior a una quemadura mayor constituye una respuesta sistémica compleja caracterizada por activación neuroendocrina sostenida, inflamación persistente y disfunción metabólica celular. Este fenómeno condiciona alteraciones profundas en múltiples sistemas orgánicos, incluyendo el cardiovascular, respiratorio, metabólico, renal, neurológico, hepático e inmunológico, lo que representa un reto significativo para el manejo anestésico perioperatorio.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Jeschke MG. Postburn hypermetabolism: past, present and future. Int JBurns Trauma. 2016;6:1-6.

  2. Finnerty CC, Herndon DN, Przkora R, Pereira CT, Oliveira HM,Queiroz DM, et al. Cytokine expression profile over time in severelyburned pediatric patients. Shock. 2006;26:13-19. doi: 10.1097/01.shk.0000223120.26394.7d.

  3. Burn injury. Nat Rev Dis Primers. 2020;6:12. doi: 10.1038/s41572-020-0152-6.

  4. Bittner EA, Shank E, Woodson L, Martyn JA. Acute andperioperative care of the burn-injured patient. Anesthesiology.2015;122:448-464.

  5. Williams FN, Herndon DN, Jeschke MG. The hypermetabolicresponse to burn injury and interventions. Clin Plast Surg.2009;36:583-596.

  6. García-Lara MÁ, Sánchez-Sagrero A, Aguilar-Águila-Martínez A,López-León NL. Manejo anestésico del paciente quemado. Rev MexAnestesiol. 2022;45:129-134. doi:10.35366/103888.

  7. Garnica-Escamilla MA, Lemus-Sandoval J, Ramírez-Martínez BN,Tamez-Coyotzin EA, Marín-Landa OM. Hipermetabolismo en elpaciente quemado. Rev Mex Anestesiol. 2021;44:211-218. doi:10.35366/101158.

  8. Porter C, Herndon DN, Sidossis LS, Børsheim E. The metabolic stressresponse to burn trauma: current understanding and therapies. Int J MolSci. 2016;17:53. doi: 10.3390/ijms17010053.

  9. Latenser BA. Critical care of the burn patient. Crit Care Med.2009;37:2819-2826.

  10. Dries DJ. Management of burn injuries. Scand J Trauma Resusc EmergMed. 2009;17:14.

  11. Stephenson SF, Esrig BC, Polk HC Jr, Fulton RL. The pathophysiologyof smoke inhalation injury. Ann Surg. 1975;182:652-660. doi:10.1097/00000658-197511000-00020.

  12. McGovern C, O’Sullivan ST. Anaesthesia for major burns. BJA Educ.2022;22:195-201.

  13. Wolfe RR. The underappreciated role of muscle in health and disease.Am J Clin Nutr. 2006;84:475-482. doi: 10.1093/ajcn/84.3.475.

  14. Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE,Herndon DN. The metabolic stress response to burn trauma. Lancet.2016;388:1417-1426.

  15. Clark A, Neyra JA, Madni T, Imran J, Phelan H, Arnoldo B, et al.Acute kidney injury after burn. Burns. 2017;43:898-908. doi: 10.1016/j.burns.2017.01.023.

  16. Herndon DN. Total burn care. 5th ed. Philadelphia: Elsevier; 2018.

  17. Subramaniyan S, Terrando N. Neuroinflammation and perioperativeneurocognitive disorders. Anesth Analg. 2019;128:781-788. doi:10.1213/ANE.0000000000004053.

  18. Halevi A, Hoisington A, Vogler TO, Stamper C, Brenner L, NajarroKM, et al. Neuroinflammation after burn injury. J Burn Care Res.2026;47:S279. doi: 10.1093/jbcr/irag033.321.

  19. Jeschke MG. Postburn hypermetabolism: past, present and future. Int JBurns Trauma. 2016;6:1-6.

  20. Finnerty CC, Herndon DN, Przkora R, Pereira CT, Oliveira HM,Queiroz DM, et al. Cytokine expression profile over time in severelyburned pediatric patients. Shock. 2006;26:13-19. doi: 10.1097/01.shk.0000223120.26394.7d.

  21. Burn injury. Nat Rev Dis Primers. 2020;6:12. doi: 10.1038/s41572-020-0152-6.

  22. Bittner EA, Shank E, Woodson L, Martyn JA. Acute andperioperative care of the burn-injured patient. Anesthesiology.2015;122:448-464.

  23. Williams FN, Herndon DN, Jeschke MG. The hypermetabolicresponse to burn injury and interventions. Clin Plast Surg.2009;36:583-596.

  24. García-Lara MÁ, Sánchez-Sagrero A, Aguilar-Águila-Martínez A,López-León NL. Manejo anestésico del paciente quemado. Rev MexAnestesiol. 2022;45:129-134. doi:10.35366/103888.

  25. Garnica-Escamilla MA, Lemus-Sandoval J, Ramírez-Martínez BN,Tamez-Coyotzin EA, Marín-Landa OM. Hipermetabolismo en elpaciente quemado. Rev Mex Anestesiol. 2021;44:211-218. doi:10.35366/101158.

  26. Porter C, Herndon DN, Sidossis LS, Børsheim E. The metabolic stressresponse to burn trauma: current understanding and therapies. Int J MolSci. 2016;17:53. doi: 10.3390/ijms17010053.

  27. Latenser BA. Critical care of the burn patient. Crit Care Med.2009;37:2819-2826.

  28. Dries DJ. Management of burn injuries. Scand J Trauma Resusc EmergMed. 2009;17:14.

  29. Stephenson SF, Esrig BC, Polk HC Jr, Fulton RL. The pathophysiologyof smoke inhalation injury. Ann Surg. 1975;182:652-660. doi:10.1097/00000658-197511000-00020.

  30. McGovern C, O’Sullivan ST. Anaesthesia for major burns. BJA Educ.2022;22:195-201.

  31. Wolfe RR. The underappreciated role of muscle in health and disease.Am J Clin Nutr. 2006;84:475-482. doi: 10.1093/ajcn/84.3.475.

  32. Porter C, Tompkins RG, Finnerty CC, Sidossis LS, Suman OE,Herndon DN. The metabolic stress response to burn trauma. Lancet.2016;388:1417-1426.

  33. Clark A, Neyra JA, Madni T, Imran J, Phelan H, Arnoldo B, et al.Acute kidney injury after burn. Burns. 2017;43:898-908. doi: 10.1016/j.burns.2017.01.023.

  34. Herndon DN. Total burn care. 5th ed. Philadelphia: Elsevier; 2018.

  35. Subramaniyan S, Terrando N. Neuroinflammation and perioperativeneurocognitive disorders. Anesth Analg. 2019;128:781-788. doi:10.1213/ANE.0000000000004053.

  36. Halevi A, Hoisington A, Vogler TO, Stamper C, Brenner L, NajarroKM, et al. Neuroinflammation after burn injury. J Burn Care Res.2026;47:S279. doi: 10.1093/jbcr/irag033.321.




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