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Idioma: Español
Referencias bibliográficas: 14
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FRAGMENTO

El propofol ha dejado de ser solamente un hipnótico intravenoso de inicio rápido y recuperación predecible. En la anestesiología actual, su valor reside en que permite hacer un ejercicio explícito de farmacocinética, farmacodinámica y lectura neurofisiológica. Ya no solo debemos preguntarnos «¿cuántos miligramos administrar?», sino «¿qué concentración objetivo persigo, en qué compartimento, con qué velocidad de aproximación, bajo qué patrón electroencefalográfico y en qué paciente?». Ese cambio conceptual redefine al propofol como una herramienta de precisión.

REFERENCIAS (EN ESTE ARTÍCULO)

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2. Glen JB. The discovery and development of propofol anesthesia: the2018 Lasker-DeBakey Clinical Medical Research Award. JAMA.2018;320:1235-1236.

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