Nepomuceno-Severiano Y

Idioma: Español
Referencias bibliográficas: 12
Paginas: 461-463
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FRAGMENTO

La anestesia total intravenosa (TIVA) basada en propofol ha evolucionado desde esquemas de dosificación por peso hacia modelos farmacocinéticos-farmacodinámicos, infusión controlada por objetivos (TCI), monitorización neurofisiológica y medicina perioperatoria de precisión.

REFERENCIAS (EN ESTE ARTÍCULO)

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2. Eleveld DJ, Colin P, Absalom AR, Struys MMRF. Pharmacokineticpharmacodynamicmodel for propofol for broad application inanaesthesia and sedation. Br J Anaesth. 2018;120:942-959.

3. Absalom AR, Schnider TW. The future of target-controlled infusion andnew pharmacokinetic models. Curr Opin Anaesthesiol. 2025;38:375-381.doi: 10.1097/ACO.0000000000001529.

4. Irwin MG, Chung CKE, Ip KY, Wiles MD. Influence of propofol-basedtotal intravenous anaesthesia on peri-operative outcome measures: anarrative review. Anaesthesia. 2020;75 Suppl 1:e90-e100.

5. Purdon PL, Pavone KJ, Akeju O, Smith AC, Sampson AL, Lee J, et al.The ageing brain: age-dependent changes in the electroencephalogramduring propofol and sevoflurane general anaesthesia. Br J Anaesth.2015;115 Suppl 1:i46-i57.

6. Mulvey DA, Rauf J, Smith J, et al. Use of processed electroencephalographyin the clinical setting. BJA Education. 2020;20:368-375.

7. Klein AA, Meek T, Allcock E, et al. Recommendations for standardsof monitoring during anaesthesia and recovery 2021. Anaesthesia.2021;76:1212-1223.

8. Cortínez LI, De la Fuente N, Eleveld DJ, Oliveros A, Crovari F,Sepulveda P, et al. Performance of propofol target-controlled infusionmodels in the obese: pharmacokinetic and pharmacodynamic analysis.Anesth Analg. 2014;119:302-310.

9. Song Y. Age-specific electroencephalography dynamics duringanesthesia: monitoring and neurocognitive implications. Anesth PainMed (Seoul). 2025;20:289-300. doi: 10.17085/apm.25375.

10. Jones KG, Lybbert C, Euler MJ, Huang J, Lunt S, Richards SV, et al.Diversity of electroencephalographic patterns during propofol-inducedburst suppression. Front Syst Neurosci. 2023;17:1172856.

11. Tan F, Cao Y, Deng Y, Chi X. Application of different infusion methodsof propofol in intravenous anesthesia: a narrative review. Dig Med Res2021;4:74.

12. Kim Y, Park J, Chung W, Jo Y, Oh C, Hong B, et al. Age-relatedelectroencephalographic delta and alpha oscillations during sedationwith target-controlled propofol infusion. J Clin Med. 2025;14:3024.