Mendoza SA, Sobrino CS, Hernández GA, Córdova PVH, Alonso LO, Sánchez DJ

Idioma: Español
Referencias bibliográficas: 49
Paginas: 411-415
Archivo PDF: 46.64 Kb.

RESUMEN

Introducción: el cáncer de colon no polipósico hereditario (CCNPH) representa de 2 a 7% de todas de las neoplasias malignas del colon, el diagnóstico se realiza por los criterios de Ámsterdam, Ámsterdam modificados y Bethesda. Objetivo: evaluar la utilidad clínica de las escalas diagnósticas para CCNPH en nuestra población y determinar las características clínicas que nos puedan predecir a un caso de CCNPH. Material y métodos: estudio retrospectivo, transversal, se incluyó a pacientes con cáncer de colon menores de 50 años en un periodo de tres años. Se recabaron los datos demográficos, antecedentes familiares, edad del diagnóstico y características del tumor. Se aplicaron los criterios de Ámsterdam, Ámsterdam modificados y Bethesda. Resultados: cincuenta y seis de 210 pacientes con cáncer de colon fueron menores de 50 años con una edad media de 38.3 años, 14.3% tenía antecedentes familiares oncológicos. En 53.6% el tumor se localizó en el colon derecho e histológicamente predominó el componente mucinoso y pobre diferenciación celular. Sólo dos pacientes cumplieron con los criterios de Ámsterdam y Ámsterdam modificados y ninguno cumplió con los criterios de Bethesda. Conclusión: la frecuencia de CCNPH en nuestra población es de 1% por los criterios de Ámsterdam y Ámsterdam modificados y 0% por los criterios de Bethesda.

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