Ramírez AR, Azcona-Cruz MI

Idioma: Español
Referencias bibliográficas: 39
Paginas: 71-75
Archivo PDF: 927.75 Kb.

RESUMEN

El manganeso (Mn) es un elemento traza requerido en mínimas cantidades para el crecimiento, desarrollo y función de los seres humanos, pero en exceso puede ser un potente neurotóxico. Es un componente normal del aire, el suelo, el agua y los alimentos; además, se utiliza en una gran variedad de productos como fuegos artificiales, baterías secas, fertilizantes, pinturas, cosméticos y aditivos en la gasolina. La principal forma de exposición al Mn es por consumo de alimentos como cereales, legumbres y frutos secos o suplementos nutricionales. Se sabe que los factores de riesgo ocupacional se incrementan en los trabajadores de fundiciones de acero o soldadores, quienes pueden presentar altos niveles de Mn en sangre. Se ha reportado que la neurotoxicidad producida por el Mn se asocia con alteraciones motoras y cognitivas conocidas como manganismo. Los mecanismos subyacentes a esta condición tóxica siguen siendo desconocidos, ya que los signos clínicos y síntomas son parecidos, mas no idénticos, a los de la enfermedad de Parkinson (EP).

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