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Colegio de Medicina Interna de México.

2020, Número S4

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Med Int Mex 2020; 36 (S4)


Proteínas

Chirino-Romo J

Idioma: Español
Referencias bibliográficas: 15
Paginas: 24-26
Archivo PDF: 266.5 Kb.


FRAGMENTO

ANTECEDENTES

Uno de los puntos clave del tratamiento nutricional de pacientes con infección por SARS-CoV-2 (COVID-19) es el aporte proteico, debido al hipercatabolismo y el desgaste calórico-proteico que suele coexistir, sobre todo en los casos graves.

Durante el estrés originado por el proceso infeccioso, el metabolismo suele alterarse y llevar energía y sustancias metabólicas esenciales a los órganos vitales, más que al tejido adiposo y muscular. Esto ocasiona estrés oxidativo, oxidación lipídica y proteica, disfunción mitocondrial y alteración de la autofagia que pueden suprimirse mediante el aporte exógeno de nutrientes, sobre todo de aminoácidos.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Wernerman J, et al. Metabolic support in the critically ill: a consensus of 19. Crit Care. 2019; 23 (1): 318. https://doi. org/10.1186/s13054-019-2597-0

  2. Singer P, et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019; 38 (1): 48-79. https:// doi.org/10.1016/j.clnu.2018.08.037

  3. Barazzoni R, et al. ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection. Clin Nutr. 2020; 39 (6): 1631-8. https://doi.org/10.1016/j.clnu.2020.03.022

  4. Caccialanza R, et al. Early nutritional supplementation in non-critically ill patients hospitalized for the 2019 novel coronavirus disease (COVID-19): Rationale and feasibility of a shared pragmatic protocol. Nutrition 2020; 74: 110835. https://doi.org/10.1016/j.nut.2020.110835

  5. CCSG-Guidance-for-COVID-19-Formatted.pdf https:// www.bda.uk.com/uploads/assets/f5215258-7a34- 4426-83620ba89f87c638/b4ec8d2c-156e-4e30- a8920619ca6e3a4d/CCSG-Guidance-for-COVID-19.

  6. Yébenes J, et al. Nutritrauma: A Key Concept for Minimising the Harmful Effects of the Administration of Medical Nutrition Therapy. Nutrients 2019; 11 (8): 1775. https:// doi.org/10.3390/nu11081775

  7. Koekkoek WK, et al. Timing of PROTein INtake and clinical outcomes of adult critically ill patients on prolonged mechanical VENTilation: The PROTINVENT retrospective study. Clin Nutr. 2019;38(2):883-90. https://doi.org/10.1016/j. clnu.2018.02.012

  8. van Zanten ARH. Changing paradigms in metabolic support and nutrition therapy during critical illness. Curr Opin Crit Care. 2018; 24 (4): 223-7. doi: 10.1097/ MCC.0000000000000519

  9. Hurt RT, et al. Summary Points and Consensus Recommendations From the International Protein Summit. Nutr Clin Pract. 2017; 32 (1_suppl):142S-51S. https://doi. org/10.1177/0884533617693610

  10. Martindale R, Patel JJ. Nutrition Therapy in the Patient with COVID-19 Disease Requiring ICU Care. 2020; 8.

  11. Lambell KJ, et al. Nutrition therapy in critical illness: a review of the literature for clinicians. Crit Care. 2020; 24 (1): 35. https://doi.org/10.1186/s13054-020-2739-4

  12. Campos LF, et al. Parecer BRASPEN/AMIB para o enfrentamento da COVID-19 em pacientes hospitalizados. Braspen J. 2020; 35 (1). http://arquivos.braspen.org/journal/ jan-mar-2020/artigos/01-Parecer-BRASPEN-COVID-19.pdf

  13. McClave SA, et al. Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2016; 40 (2): 159-211. 10.1177/0148607115621863

  14. Handu D, et al. Malnutrition Care during the COVID-19 Pandemic: Considerations for Registered Dietitian Nutritionists Evidence Analysis Center. J Acad Nutr Diet. 2020;S2212267220304810. https://doi.org/10.1016/j. jand.2020.05.012

  15. Draft-CCP-Intensive-Care-Nutrition-Support-Algorithm-in- HSE-format_V10_Mar-2020.pdf.




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