2021, Number 1
Endoscopic management of gallbladder adenocarcinoma. Case report
Fernández-González VC, Hernández-Lozada VH
Language: Spanish
References: 9
Page: 28-33
PDF size: 265.88 Kb.
ABSTRACT
Introduction: Gallbladder adenocarcinoma is a rare condition that usually presents with no symptoms upon presentation and has a poor prognosis. The main known risk factor for the development of adenocarcinoma is the association between chronic inflammation caused by gallstones and because these two entities usually present together it makes it difficult to recognize adenocarcinoma at its early stages. Up to 70% of cases are incidentally found upon examination by the pathologist and present at advance stages with a 5% survival rate at five years. Case presentation: 75-year-old male that presents with a 1-month history of right hypochondrium pain with generalized jaundice and direct bilirubin elevation. A diagnosis of acute on chronic cholecystitis was made with a high suspicious of choledocholithiasis, cholecystectomy by laparoscopy was performed following a endoscopic retrograde cholangiopancreatography (ERCP) intraoperative which found significant biliary dilation and stricture that was managed with placement of a biliary stent. Days after it was reported by the pathologist the incidental finding of gallbladder adenocarcinoma. Conclusion: Gallbladder adenocarcinoma presents in most cases with an advance staging disease. Therapeutic options for these patients are limited because of the lack of research demonstrating the benefits on survival rates, that is why is important that the main therapeutic approach focuses on palliative care measurements and relieved of the obstructive symptoms that often accompany this disease so that we can improve patient life style.REFERENCES
Sung YN, Song M, Lee JH, Song KB, Hwang DW, Ahn CS. Validation of the 8th edition of the American Joint Committee on Cancer staging system for gallbladder cancer and implications for the follow-up of patients without node dissection. Cancer Res Treat. 2020; 52: 455-468. Available in: https://pubmed.ncbi.nlm.nih.gov