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2022, Number 4

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Acta Med 2022; 20 (4)

Q fever as part of the management of fever of unknown origin

Salvador IIJ, Pizaña DA, Alva ANV, Huerta EMG
Full text How to cite this article 10.35366/107121

DOI

DOI: 10.35366/107121
URL: https://dx.doi.org/10.35366/107121

Language: Spanish
References: 7
Page: 350-352
PDF size: 190.80 Kb.


Key words:

Q fever, Coxiella burnetii, aerosols, indirect immunofluorescia, doxycycline.

ABSTRACT

Q fever is an infectious disease, first described by Derrick. In 1999, Q fever became a notifiable disease in the United States (US), due to its potential as an agent of bioterrorism. The incidence is believed to be higher, however, there are no specific data to conclude this, designating it as an underdiagnosed pathology. The most common clinical presentation ranges from asymptomatic, persistent fever, asthenia, adynamia, to severe pneumonia and hepatitis. The best available diagnostic method is indirect immunofluorescence (IFA) for the detection of antibody titers. Specific treatment is an antibiotic from the tetracycline group; doxycycline is preferred and should be started promptly and appropriately on suspicion.


REFERENCES

  1. Derrick EH. "Q" fever, a new fever entity: clinical features, diagnosis and laboratory investigation. Med J Aust. 1937; 2: 281-299.

  2. Burnet FM, Freeman M. Experimental studies on the virus of "Q" fever. Med J Aust. 1937; 2: 299-305.

  3. Davis G, Cox HR. A filterpassing infectious agent isolated from ticks: isolation from Dermatocentor andersoni, reaction in animals, and filtration experiments. Public Health Rep. 1938; 53 (52): 2259-2267.

  4. Araujo J, Sifuentes J, Bobadilla JM et al. ¿Qué sabemos acerca de la fiebre Q en México? Rev Invest Clin. 2012; 64 (6): 541-545.

  5. Eldin C, Mélenotte C, Mediannikov O et al. From Q Fever to Coxiella burnetii infection: a paradigm change. Clin Microbiol Rev. 2017; 30 (1): 115-190.

  6. Anderson A, Bijlmer H, Fournier PE et al. Diagnosis and management of Q fever-United States, 2013:recommendations from CDC and the Q fever working group. MMWR Recomm Rep. 2013; 62 (RR-03): 1-30.

  7. Dahlgren FS, McQuiston JH, Massung RF, Anderson AD. Q fever in the United States: summary of case reports from two national surveillance systems, 2000-2012. Am J Trop Med Hyg. 2015; 92 (2): 247-255.




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Acta Med. 2022;20