Villanueva OGS, Ortiz AJI, Ruiz EJA, Parral PJM, Cázares MHM

Language: Spanish
References: 7
Page: 299-302
PDF size: 394.99 Kb.

ABSTRACT

Cryptococcosis is an infectious disease with worldwide distribution, with varied clinical manifestations, caused by two capsulated yeasts of the Cryptococcus genus: C. neoformans and C. gattii. Cryptococcosis can present with a variety of skin and soft tissue manifestations, including acneiform lesions, purpura, vesicles, nodules, abscesses, ulcers, granulomas, pustules, sinus drainage, and cellulitis. Most skin and soft tissue manifestations occur as disseminated disease, which is evident in 10 to 15% of patients with systemic cryptococcosis. It has a mortality of 16 to 24% and continues to be a common and serious infection in immunosuppressed patients.
We report a 43-year-old male with a history of Hodgkin’s lymphoma, anxiety and depression. His condition begins with fever, cough, dyspnea, accompanied by neurological deterioration with the presence of skin lesions on the anterior chest and face, characterized by umbilical papular acneiform lesions in the center. Biopsies of these lesions were taken and cutaneous cryptococcosis was diagnosed, as well as cytological and cytochemical tests of cerebrospinal fluid compatible with mycotic meningitis. Treatment with fluconazole was started, however, he presented a torpid evolution with subsequent death.

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