medigraphic.com
SPANISH

Acta Médica Grupo Angeles

Órgano Oficial del Hospital Angeles Health System
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
    • Names and affiliations of the Editorial Board
  • Policies
  • About us
    • Data sharing policy
    • Stated aims and scope
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2023, Number 2

<< Back Next >>

Acta Med 2023; 21 (2)

Polymyositis associated with interstitial pneumopathy in the elderly

Arellano AJG, Arellano GG, Domínguez CLG
Full text How to cite this article 10.35366/110267

DOI

DOI: 10.35366/110267
URL: https://dx.doi.org/10.35366/110267

Language: Spanish
References: 4
Page: 170-172
PDF size: 164.72 Kb.


Key words:

polymyositis, dropped head syndrome, interstitial lung disease.

ABSTRACT

Introduction: polymyositis, a relatively uncommon autoimmune disorder, develops due to abnormal activation of cytotoxic T lymphocytes and macrophages against muscle antigens presenting as a proximal myopathy is associated with interstitial lung disease in 10 to 30% of patients. Case report: 76-year-old male with a slow evolution of eight months, characterized by fatigue, weight loss of 12 kilos, and increasing weakness in cervical paravertebral muscles and muscles of the shoulder and pelvic girdles. Laboratory showed elevated muscle enzymes, positive Anti J-1 antibodies, consistent EMG data, and a biopsy confirming polymyositis, associated with interstitial lung disease. Steroid treatment and rehabilitation were started, obtaining significant clinical improvement at three weeks. Conclusion: since polymyositis is not frequent, the diagnosis is reached by exclusion mainly when the symptomatology and the tomographic images coincide during COVID-19.


REFERENCES

  1. Sarwar A, Dydyk AM, Jatwani S. Polymyositis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022.

  2. Kesserwani H. Predominant neck extensor muscle weakness: a rare manifestation of idiopathic polymyositis. Cureus. 2020; 12 (6): e8735.

  3. Shao T, Shi X, Yang S, Zhang W, Li X, Shu J et al. Interstitial lung disease in connective tissue disease: a common lesion with heterogeneous mechanisms and treatment considerations. Front Immunol. 2021; 12: 684699.

  4. Hoyos N, Casanova A, Sánchez S, Valenzuela C, García A, Girón RM. Polymyositis and interstitial lung disease with a favorable response to corticosteroids and methotrexate. Arch Bronconeumol. 2007; 43 (11): 636-639.




Figure 1
Figure 2
Figure 3

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Acta Med. 2023;21