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Federación Mexicana de Ginecología y Obstetricia, A.C.

2023, Number 03

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Ginecol Obstet Mex 2023; 91 (03)

Diagnosis and surgical treatment of a patient with gestational trophoblastic neoplasia

Lozano-Vidal M, Rodríguez Sánchez-Reyman J, Machuca-Aguado J, Sánchez-Bernal ML, Martínez-Roche MI

Language: Spanish
References: 17
Page: 210-217
PDF size: 299.23 Kb.


ABSTRACT

Background: Gestational trophoblastic neoplasia is one of a group of conditions resulting from abnormal trophoblast proliferation with capacity for invasion and metastasis.
Clinical case: 42-year-old asymptomatic patient with ultrasound suspicion of hydatidiform mole. Uterine curettage and anatomopathological study confirmed the diagnosis of complete hydatidiform mole. With the consecutive quantification of three elevations of β-HCG a diagnosis of gestational trophoblastic neoplasia was made. It was staged as stage I, low-risk, and the patient agreed to hysterectomy plus bilateral salpingectomy. At subsequent follow-up the patient was found to be asymptomatic, with negative serial determinations of β-HCG and vaginal ultrasound scans without findings.
Conclusion: Hysterectomy with bilateral salpingectomy may be the definitive treatment in selected cases of trophoblastic neoplasia. The available evidence is scarce and further research is needed in this field.


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