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2023, Number 3

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Acta Med 2023; 21 (3)

Intratimpanic dexamethasone as first line therapy for sensorineural sudden hearing loss

Guakil HA, Kuri GA, García EB
Full text How to cite this article 10.35366/111345

DOI

DOI: 10.35366/111345
URL: https://dx.doi.org/10.35366/111345

Language: Spanish
References: 21
Page: 236-240
PDF size: 168.33 Kb.


Key words:

otolaryngology, sudden hearing loss, intratympanic injection.

ABSTRACT

Introduction: sensorineural sudden hearing loss is an otological emergency characterized by a loss of at least 30 dB in three or more continuous audiometric frequencies in 72 hours or less. Objective: determine if intratympanic dexamethasone is effective as a first-line therapy in idiopathic sensorineural sudden hearing loss. Material and methods: a retrospective, transversal, and descriptive review of patients diagnosed with idiopathic sensorineural sudden hearing loss treated with intratympanic dexamethasone injection 8 mg/2 mL, applied daily for five days. Results: during the study, 104 patients treated with intratympanic dexamethasone injection as a first-line therapy were reviewed, 64% of which had a complete recovery, 10% a partial recovery, and 26% had no comeback. The average hearing improvement was 19 decibels, although an association with age, sex, affected side, and comorbidities wasn't statistically significant. Regarding intratympanic injection-associated complications: 21% of patients reported acute, self-limited dizziness or vertigo. One patient presented acute otitis media, requiring oral antibiotics. No other complications were found. Conclusions: intratympanic dexamethasone injection is an effective first-line treatment for idiopathic sensorineural sudden hearing loss, with a low incidence of associated complications.


REFERENCES

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Acta Med. 2023;21