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2003, Number s1

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Arch Cardiol Mex 2003; 73 (s1)

Therapeutical approach of intracoronary thrombus

Villavicencio FR
Full text How to cite this article

Language: Spanish
References: 7
Page: 153-157
PDF size: 58.57 Kb.


Key words:

Percutaneous transluminal coronary angioplasty, Intracoronary thrombus, X-Sizer catheter.

ABSTRACT

Coronary thrombus during percutaneous transluminal coronary angioplasty setting is a therapeutic challenge. Coronary thrombus in acute coronary syndromes has been associated with an increase of major adverse cardiac events, which have relationship with distal embolization and “no-reflow” phenomenon. What’s just time to take a decision for therapeutic approach of coronary thrombus? Basically, this question it depends of two main factors: clinical condition of the patient and the size of coronary thrombus. Therefore, if the lesion contains small thrombus independently of the clinical condition of the patient it’s very sure that the angiographic result will be very adequate with catheter ballon and stenting. However, by the other side if thrombus is large and there was no time for intravenous infusion of IIb-IIIa inhibitors, because of patient unstability (serious arrhythmia or hemodynamic collapse) is recommendable to use some devices of thrombectomy + aspiration with the purpose to diminish thrombus burden and avoid complications of distal embolization and “no-reflow” phenomenon. X-Sizer catheter is a very versatile device who combines purposes of thrombectomy plus aspiration. Our experience in 42 patients with acute coronary syndromes showed that its use is sure and feasible with a very low rate of ischemic complications and TIMI 3 flow restoration in 80% of all patients. Therapeutical approach of coronary thrombus must be based in the experience and the knowledge of some devices for thrombectomy plus aspiration.


REFERENCES

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  2. Deligonul V, Gabliani GI, Caroles DG: Percutaneous transluminal coronary angioplasty in patients with intracoronary thrombus. Am J Cardiol 1988; 62: 474-476.

  3. Mooney MR, Fishman-Mooney J, Godenberg: Percutaneous transluminal coronary angioplasty in the setting of large intracoronary thrombus. Am J Cardiol 1990; 65: 427-431.

  4. Scwartz L, Seidelin PH: Antithrombotic and Thrombolytic Therapy in patients undergoing coronary artery interventions: A Review. Progr Cardiovasc Dis 1995; 38: 67-86.

  5. O’ Neill WW, Sketch MH, Steenkiste A, Detre K: New Device Intervention in the treatment of intracoronary thrombus: report of the NACI registry. Circulation 1993; 88: 1-595.

  6. Mark Doorisi M, Mellisa Hoffman M, Glazier S, Juran N, Grines C, O’Neill W, Safian R: Comparative results of transluminal extraction coronary atherectomy in saphenous vein graft lesion with and without thrombus. J Am Coll Cardiol 1995; 25: 1700-1705.

  7. Ischinger T: Thrombectomy with the X-Sizer catheter system in the coronary circulation: initial results from a multicenter study. J Invasive Cardiol 2001; 13 (2): 81-88.




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C?MO CITAR (Vancouver)

Arch Cardiol Mex. 2003;73