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Organo Oficial de la Sociedad Mexicana de Urología

2023, Number 3

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Rev Mex Urol 2023; 83 (3)

Predictors of delayed kidney graft function: a retrospective study

Ornelas-Aguirre JM, Jiménez-Rodríguez MJ, Arias-Constantino JM, Gurrola-Castillo A, Ochoa-Parra KA

Language: Spanish
References: 35
Page: 1-15
PDF size: 491.43 Kb.


ABSTRACT

Objective: To know the frequency and factors associated with delayed graft function (DGF) in a tertiary care center in northwestern Mexico.
Methods: Retrospectively, transplanted patients from 2011 to 2017 and their association to DGF were reviewed. The DGF was defined as a case that required dialysis within the first post-transplant week. For the analysis of the variables involved in DGF, logistic regression was used.
Results: Delayed graft function occurred in 11% (CI 95%, 7 to 15) of 199 transplants studied. The risk factors associated with DGF included: combined renal replacement therapy (OR: 3.50; CI 95%: 1.39 to 8.78; p=0.005), cadaveric donor (OR: 8.06; CI 95%: 1.82 to 35.53; p=0.001), cardiovascular disease (OR: 4.32; CI 95%: 0.74 to 25.12; p=0.07), and acute rejection (OR: 2.78; CI 95%: 0.98 to 7.90; p=0.04). The multiva- riate analysis demonstrated combined renal replacement therapy (OR: 3.34; p=0.01) and cadaveric donor (OR: 8.02; p=0.007) as independent risk factors for DGF (OR: 8.02; p=0.007).
Conclusions: The factors associated with DGF observed in the present study are related to the kidney recipient and the donor. Further prog- nostic studies that permit the discovery of the influence that diverse known factors have in the development of DGF and the prognosis for the transplanted organ are required.


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