Sánchez GJC, Arias MLE, Espinosa MPV, Ruíz CCA, Rivero GD

Language: Spanish
References: 8
Page: 961-966
PDF size: 255.54 Kb.

ABSTRACT

Background: Lupus anticoagulant-hypoprothrombinemia syndrome is a disease in which antiprothrombin antibodies exist in addition to lupus anticoagulant, leading to acquired factor II deficiency or hypoprothrombinemia. This results in a greater predisposition to suffer hemorrhagic events.
Clinical case: A 58-year-old male patient diagnosed with antiphospholipid syndrome with thrombotic and haemorrhagic events with persistent atrial fibrillation and venous insufficiency record, who entered to the internal medicine department due to anemic syndrome and in whom the bleeding algorithm was approached, showing a scintigraphy with positive erythrocytes for duodenal bleeding, as well as several thrombosis events during his admission to the hospital. Taking in consideration that the patient could have been an autoimmune disease carrier, antiphospholipid antibody determinations were carried out, which resulted positive. A bleeding tendency predominated from the beginning as well as prolonged clotting time, therefore, the lupus anticoagulanthypoprothrombinaemia syndrome was diagnosed.
Conclusions: The type of lupus anticoagulant-hypoprothrombinemia syndrome associated with autoimmune diseases is more aggressive and hemorrhagic complications are a common feature.

REFERENCES

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