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Colegio de Medicina Interna de México.

2023, Number 6

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Med Int Mex 2023; 39 (6)

Rapidly progressive focal and segmental glomerulonephritis associated to urachus adenocarcinoma, an underestimated paraneoplastic syndrome

García HA, Pérez RE

Language: Spanish
References: 17
Page: 967-971
PDF size: 248.89 Kb.


ABSTRACT

Background: Paraneoplastic glomerulopathies are a scarce manifestation of oncologic diseases. Tumors frequently associated with kidney disease include gastrointestinal neoplasms and lung carcinomas. The most commonly subtypes in men are extracapillary, membranous and mesangiocapillary nephropathy, and minimal change disease in women.
Clinical case: A 40-year-old male patient in which a rapidly progressive focal and segmental glomerulosclerosis associated with urachal adenocarcinoma was found during haematuria approach.
Conclusions: Nowadays no study has been able to determine the true incidence of glomerular impairment in cancer, but a link has been identified between several particular glomerulopathies and specific cancers.


REFERENCES

  1. Ronco PM. Paraneoplastic glomerulopathies: new insightsinto an old entity. Kidney Int 1999; 56 (1): 355-377. https://doi.org/10.1046/j.1523-1755.1999.00548.x.

  2. Galloway J. Remarks on Hodgkin’s disease. Br Med J1922; 2 (3234): 1201-1208. https://doi.org/10.1136/bmj.2.3234.1201.

  3. Kodner C. Diagnosis and management of nephrotic syndromein adults. Am Family Phys 2016; 93 (6): 479-485.

  4. Bacchetta J, Juillard L, Cochat P, Droz JP. Paraneoplasticglomerular diseases and malignancies. Crit Rev Oncology/Hematology 2009; 70 (1): 39-58. https://doi.org/10.1016/j.critrevonc.2008.08.003

  5. Lefaucheur C, Stengel B, Nochy D, Martel P, Hill GS, JacquotC, Rossert J, GN-PROGRESS Study Group (2006). Membranousnephropathy and cancer: Epidemiologic evidenceand determinants of high-risk cancer association. KidneyInt 2006; 70 (8): 1510-1517. https://doi.org/10.1038/sj.ki.5001790.

  6. Rosenberg AZ, Kopp JB. Focal segmental glomerulosclerosis.Clin J Am Soc Nephrol CJASN 2017; 12 (3): 502-517.https://doi.org/10.2215/CJN.05960616.

  7. Fogo AB. Causes and pathogenesis of focal segmentalglomerulosclerosis. Nature Rev Nephrology 2015; 11 (2):76-87. https://doi.org/10.1038/nrneph.2014.216.

  8. Ishida I, Hirakata H, Kanai H, Nakayama M, Katafuchi R,Oochi N, Okuda S, Fujishima M. Steroid-resistant nephroticsyndrome associated with malignant thymoma. ClinicalNephrol 1996; 46 (5): 340-346.

  9. Endoh M, Nishizawa K, Suga T, Miura M, Kaneshige H,Tomino Y, Nomoto Y, Sakai H. Focal segmental glomerulosclerosisassociated with a pheochromocytoma. Tokai JExp Clin Med 1984; 9 (3): 191-197.

  10. Absy M, Gazzawi B, Amoah E. Focal and segmentalglomerulosclerosis associated with malignantmesothelioma. Nephron 1992; 60 (2): 250. https://doi.org/10.1159/000186756.

  11. Jayasena SD, Woolfson RG, Griffiths MH, Neild GH. Nephroticsyndrome, malignant thymoma, and myasthenia gravis.Case report and review of the literature. Am J Nephrol 1995;15 (4): 361-363. https://doi.org/10.1159/000168865.

  12. Kiss B, Magyarlaki T, Buzogány I, Fazekas A, Sükösd F, NagyJ. A felnöttkori vesecarcinomát kísérö paraneoplasiás nephropathia(immunológiai és klinikopatológiai tanulmány)[Paraneoplastic nephropathy associated with adult renalcarcinoma (immunologic and clinicopathologic study)].Orvosi hetilap 1999; 140 (2): 75-80.

  13. Konoshita T, Itoh M, Hatakeyama S, Hirata M, Koni I, MiyazakiR, Tofuku Y, Mabuchi H. Nephrotic syndrome due tofocal glomerulosclerosis and undifferentiated carcinoma.Clin Nephrol 2002; 54 (5): 404-408.

  14. Feriozzi, S, Giannakakis K, Ranalli TV, Pofi E, Gomes V,Ancarani E. Renal oncocytoma associated with necrotizingglomerulonephritis. Renal Failure 2006; 28 (2): 181-183.https://doi.org/10.1080/08860220500531229.

  15. The HS, Halim AG, Soehardy Z, Fauzi AR, Kong CT. Molarpregnancy and glomerulonephritis. Med J Malaysia 2006;61 (3): 361-362.

  16. Lin FC, Chen JY, Yang AH, Chang SC. The association ofnon-small-cell lung cancer, focal segmental glomerulosclerosis,and platelet dysfunction. Am J Med Sci 2002;324 (3): 161-165. https://doi.org/10.1097/00000441-200209000-00008.

  17. Loi S, Perry GJ, Standish H, Dowling J. Glomerulosclerosis:a paraneoplastic phenomenon? Nephrology (Carlton, Vic.)2004; 9 (6): 387-391. https://doi.org/10.1111/j.1440-1797.2004.00328.x.




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