García-Hernández A, García-Valdés L, García-Ramírez LI, González HLA

Language: Spanish
References: 16
Page: 292-295
PDF size: 175.06 Kb.

ABSTRACT

Background: erythrasma is a superficial skin infection caused by Corynebacterium minutissimum (a Gram-positive, non-sporeforming bacillus). It can be misdiagnosed as a mycosis. It has a benign and chronic course. The main risk factors are type 2 diabetes mellitus, geriatric patients, immunocompromised patients, obesity, hyperhidrosis, and living in tropical climates. The interdigital form is the most common. This study aimed to determine the prevalence of erythrasma in people living with HIV and its comparison with the CD4 level.
Materials and methods: descriptive, prospective, and crosssectional study in subjects living with HIV, of both sexes, over 18 years of age, who attended their follow-up appointments in the hiv unit of the Civil Hospital of Guadalajara Fray Antonio Alcalde within the period from July 1, 2022, to November 30, 2022. The diagnosis of erythrasma was made with Wood’s light and with Gram stain from scale or macerated skin of the interdigital area of the feet.
Results: of 525 participants, we found 100 subjects (19%) with interdigital erythrasma; within this group, only 55% observed coral red with fluorescence under Wood’s light, and Gram stain was performed, observing the presence of corynebacteria in patients who did not show fluorescence under Wood’s light (45%). The mean age of the patients was 40 years. The main clinical signs and symptoms of erythrasma were scaling, erythema, and pruritus. On the other hand, we found no correlation between the level of CD4+ T lymphocytes and the presence of erythrasma.
Conclusions: interdigital erythrasma is common in immunocompromised patients. In our population, 19% of patients had erythrasma, sharing clinical signs and symptoms with tinea pedis, confirming that these pathologies can easily be confused. No statistically significant correlation was observed between the CD4+ T lymphocyte count and the presence of interdigital erythrasma.

REFERENCES

1. Dunn C, Applebaum DS y Dao H Jr, Widespread hyperpigmentedrash present for 1 year, jaad Case Rep 2018; 4(8):743-5.

2. Andrade-Morelos LE, Contreras-Barrera ME y Arenas R, Eritrasma:estudio en 31 pacientes jóvenes con infección por vih, MedInt Méx 2015; 31:13-8.

3. Morales-Trujillo ML, Arenas R y Arroyo S, Eritrasma interdigital:datos clínicos, epidemiológicos y microbiológicos, Actas Dermosifiliogr2008; 99(6):469-73.

4. Gruenstein D y Levitt JO, Erythrasma in 4 skin of color patientswith hidradenitis suppurativa, jaad Case Rep 2021; 13:127-9.

5. Svejgaard E, Christophersen J y Jelsdorf HM, Tinea pedis anderythrasma in Danish recruits. Clinical signs, prevalence, incidence,and correlation to atopy, J Am Acad Dermatol 1986;14(6):993-9.

6. Groves JB, Nassereddin A y Freeman AM, Erythrasma, Stat-Pearls, Treasure Island (FL), StatPearls Publishing, 8 de agostode 2022.

7. Sariguzel FM, Koc AN, Yagmur G y Berk E, Interdigital foot infections:Corynebacterium minutissimum and agents of superficialmycoses, Braz J Microbiol 2014; 45(3):781-4.

8. Instituto Nacional de Estadística y Geografía (inegi), Estadísticasa propósito del día mundial de la lucha contra el vih/sida(1 de diciembre). Disponible en: https://www.inegi.org.mx/app/saladeprensa/noticia.html?id=7799.

9. Dyer JM y Foy VM, Revealing the unseen: a review of Wood’slamp in dermatology, J Clin Aesthet Dermatol 2022; 15(6):25-30.

10. Mattox TF, Rutgers J, Yoshimori RN y Bhatia NN, Nonfluorescenterythrasma of the vulva, Obstet Gynecol 1993; 81(5 Pt 2):862-4.

11. Somerville DA, Seville RH, Cunningham RC, Noble WC y SavinJA, Erythrasma in a hospital for the mentally subnormal, Br JDermatol 1970; 82(4):355-60.

12. Masood M, Usatine RP y Heath CR, Erythrasma, Cutis 2022;110(6):338-9.

13. Inci M, Serarslan G, Ozer B et al., The prevalence of interdigitalerythrasma in southern region of Turkey, J Eur Acad DermatolVenereol 2012; 26(11):1372-6.

14. Sindhuphak W, MacDonald E y Smith EB, Erythrasma. Overlookedor misdiagnosed?, Int J Dermatol 1985; 24(2):95-6.

15. Cochran RJ, Rosen T y Landers T, Topical treatment for erythrasma,Int J Dermatol 1981; 20(8):562-4.

16. Peñaloza MJA y López NA, Corinebacteriosis cutánea, Rev CentDermatol Pascua 2001; 10(3):141-6.