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2024, Number 08

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Med Int Mex 2024; 40 (08)

Mucormycosis: 5-year retrospective study in a third level hospital in Mexico City

González RC, González IM, Duran JSE, Hernández GJG, Guerrero MB, Arenas GR
Full text How to cite this article

Language: Spanish
References: 20
Page: 472-478
PDF size: 310.29 Kb.


Key words:

Mucormycosis, Incidence, Mortality, Diabetes, Immunosuppressed, Zygomycetes, COVID-19.

ABSTRACT

Objective: To determine the incidence, risk factors, clinical findings and outcome of patients at Hospital Juarez of Mexico.
Materials and Methods: Retrospective, observational, cross-sectional, non-experimental, single-center and analytical study was done including the records of patients with direct examination, culture or histopathological study positive for mucormycosis. The incidence by year and demographic and clinical characteristics were studied from January 2017 to December 2022 at the Hospital Juarez of Mexico.
Results: A total of 14 patients with mucormycosis were identified. The median age was 51 years, and the majority were women (n = 9). The site of involvement was rhinoorbito- cerebral mucormycosis in the entire sample. Eleven patients had uncontrolled diabetes mellitus. Annual cases of mucormycosis increased notably at the end of the COVID-19 pandemic during 2022.
Conclusions: Mucormycosis is an invasive fungal disease most seen in immunocompromised patients. In this study, its highest prevalence was in decompensated diabetes mellitus and the clinical variety was rhino-orbito-cerebral. An increase was noted at the end of the COVID-19 pandemic.


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Med Int Mex. 2024;40