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Colegio de Medicina Interna de México.

2024, Number 11

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Med Int Mex 2024; 40 (11)

Clinical characterization of patients undergoing heart transplantation and the need for post-surgical extracorporeal membrane oxygenation. 10-year experience

Portilla KMA, Correa VV, Restrepo MM, Muñoz PY, Hidalgo OJE, Cañas AEM

Language: Spanish
References: 44
Page: 735-746
PDF size: 360.75 Kb.


ABSTRACT

Objective: To describe the clinical characteristics, comorbidities, and perioperative complications of heart transplant patients and those who required extracorporeal membrane oxygenation.
Materials and Methods: Descriptive and longitudinal study conducted from January 2013 to December 2022 at the Clinica Cardio VID in Medellin, Colombia, in heart transplant patients. Study parameters: perioperative clinical conditions, morbidity and characteristics of the subgroup requiring extracorporeal membrane oxygenation. Descriptive statistics and Kolmogorov-Smirnov test were used to analyze the distribution of continuous quantitative variables.
Results: We studied 209 patients, 141 male (71.3%) and 68 (28.7%) female, with a median age of 50 years. Median extracorporeal circulation: 151.1 minutes, aortic clamping 220 minutes, waiting time for extracorporeal membrane oxygenation 13 hours, stay in extracorporeal oxygenation 5 days and stay in intensive care unit 8 days. Comorbidities: arterial hypertension (44.5%) and atrial fibrillation (20.6%). During the 72 hours after transplantation, 13.9% required veno-arterial extracorporeal membrane oxygenation; mortality 3.8% (n = 8). The subgroup requiring extracorporeal membrane oxygenation had few differences from the study population.
Conclusions: The similarities and differences with the international literature highlight the importance of extracorporeal membrane oxygenation in the treatment of cardiac transplant dysfunction and the need for continuous improvement in cardiac transplant programs, even in the most complex medical centers.


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