2024, Number 1-4
<< Back Next >>
Rev Mex Cir Endoscop 2024; 25 (1-4)
Histological finding of neuroendocrine neoplasm after appendectomy. Case report
Cazares-Montañez JE, Soto-Ortega LE, Domínguez-Cabrera G, Alvear-Zamora EI, Reyes-Moctezuma MA
Language: Spanish
References: 13
Page: 14-19
PDF size: 331.45 Kb.
ABSTRACT
Appendiceal tumors are a pathological condition, commonly asymptomatic, non-frequent and only histopathologicallly diagnosed, mostly after appendectomies; less than 1% of all appendectomies performed. Among these, neuroendocrine tumors are the most frequently found. Surgical treatment depends on certain characteristics of the tumor (size, margins, lymphovascular or peri neural invasion). The aim of the article is to describe the case of a male admitted to emergency room with acute abdominal pain, caused by acute appendicitis and surgically operated; finally, histopathologically diagnosed as a well-differentiated neuroendocrine tumor Grade-I. This type of tumor represents a diagnostic and therapeutic challenge, since the surgical decision implies the most of the treatment, which will be discussed in this article.
REFERENCES
Moertel CG, Weiland LH, Nagorney DM, Dockerty MB. Carcinoid tumor of the appendix: treatment and prognosis. N Engl J Med. 1987; 317: 1699-1701. doi: 10.1056/NEJM198712313172704.
Díaz-Rivera MC, Buitrago-Toro K, Gonzales P. Tumor carcinoide del apéndice cecal: cuando un hallazgo incidental modifica drásticamente el pronóstico y tratamiento del paciente. Rev Col Gastroenterol. 2017; 32: 72-74. doi:10.22516/25007440.133.
Rorstad O. Prognostic indicators for carcinoid neuroendocrine tumors of the gastrointestinal tract. J Surg Oncol. 2005; 89: 151.
Zhang HW, Jiang Y, Huang ZY, Zhou XC. Analysis of surgical treatment of appendix neuroendocrine neoplasms—17 years of single-center experience. World J Surg Onc. 2023; 21: 150. doi: 10.1186/s12957-023-03025-6.
Mohamed A, Wu S, Hamid M, Mahipal A, Cjakrabarti S, Bajor D et al. Management of appendix neuroendocrine neoplasms: insights on the current guidelines. Cancers (Basel). 2022; 15: 295. doi: 10.3390/cancers15010295.
Connor SJ, Hanna GB, Frizelle FA. Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies. Dis Colon Rectum. 1998; 41: 75.
Cai W, Tan Y, Ge W, Ding K, Hu H. Pattern and risk factors for distant metastases in gastrointestinal neuroendocrine neoplasms: a population-based study. Cancer Med. 2018; 7: 2699-2709.
Pape UF, Niederle B, Costa F, Gross D, Kelestimur F, Kianmanesh R et al. ENETS consensus guidelines for neuroendocrine neoplasms of the appendix (excluding goblet cell carcinomas). Neuroendocrinology. 2016; 103: 144-152. doi: 10.1159/000443165.
Glasgow SC, Gaertner W, Stewart D, Davids J, Alavi K, Paquette IM et al. The American Society of Colon and Rectal Surgeons, clinical practice guidelines for the management of appendiceal neoplasms. Dis Colon Rectum. 2019; 62: 1425-1438.
Landry CS, Woodall C, Scoggins CR, McMasters KM, Martin RC 2nd. Analysis of 900 appendiceal carcinoid tumors for a proposed predictive staging system. Arch Surg. 2008; 143: 664.
Boudreaux JP, Klimstra DS, Hassan MM Woltering EA, Jensen RT, Goldsmith SJ et al. The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix, and Cecum. Pancreas. 2010; 39: 753.
Saponjski J, Macut D, Sobic-Saranovic D, Ognjanovic S, Bozic Antic I, Pavlovic D et al. Somatostatin receptor scintigraphy in the follow up of neuroendocrine neoplasms of appendix. World J Clin Cases. 2020; 8: 3697-3707. doi: 10.12998/wjcc.v8.i17.3697.
Paluri RK, Killeen RB. Neuroendocrine Tumor Lu-177-Dotatate Therapy. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK587368/