González-García N, Jiménez-Flores GL, Rojas-Trolle V, Olivar-López V, López-Mendoza L, Alvarado-Contreras AK

Language: Spanish
References: 11
Page: 173-178
PDF size: 382.02 Kb.

ABSTRACT

Introduction: viruses represent the most frequent cause of acute respiratory diseases. After COVID 19 pandemic, infectious agents and their seasonal behavior chnged.
Objective: compare the outcomes and severity of patients with acute respiratory infection of viral etiology between the 2022-2023 and 2023-2024 seasons.
Material and methods: observational, analytical, prospective and cross-sectional study. Patients from 0 to 17 years 11 months of age with acute respiratory infection with a positive viral panel who attended the Pediatric Emergency Department were included.
Results: 833 patients were included, 64 less compared to the previous season. 429 (51%) male; 597 (71%) had comorbidities. Admission to the PICU increased 2.4%, as did mortality (2.1%), associated with respiratory syncytial virus infection. Rhinovirus/ enterovirus and respiratory syncytial virus were reported most frequently.
Conclusions: respiratory syncytial virus was determined as the main causal agent of infections that require admission to the Pediatric Intensive Care Unit, mechanical ventilation and mortality, the analysis of the initial clinical presentation facilitate us the prediction of severity and let us improve the management.

REFERENCES

1. Ma X, Conrad T, Alchikh M, Reiche J, Schweiger B, Rath B. Canwe distinguish respiratory viral infections based on clinical features?A prospective pediatric cohort compared to systematic literaturereview. Rev Med Virol. 2018 Sep; 28(5):e1997.

2. Zhu G, Xu D, Zhang Y, Wang T, Zhang L, Gu W, Shen M. (2021).Epidemiological characteristics of four common respiratory viralinfections in children. Virology Journal, 18, 1-5

3. INEGI, Estadísticas de Defunciones Registradas 2021.

4. Kandeel, A., Fahim, M., Deghedy, O., H. Roshdy, W., K. Khalifa,M., El Shesheny, R., Abdelghaffar, K. (2023). Multicenter study todescribe viral etiologies, clinical profiles, and outcomes of hospitalizedchildren with severe acute respiratory infections, Egypt2022. Scientific Reports, 13(1), 21860.

5. Moriyama, M., Hugentobler, W. J., & Iwasaki, A. (2020). Seasonalityof respiratory viral infections. Annual review of virology, 7, 83-101.

6. Tang, M, Dong, W., Yuan, S., Chen, J, Lin, J., Wu, J, Zhang,L. (2023). Comparison of respiratory pathogens in children withcommunity-acquired pneumonia before and during the COVID-19 pandemic. BMC pediatrics, 23(1), 535.

7. Habbous S., Hota S., Allen V. G., Henry M., Hellsten E. (2023).Changes in hospitalizations and emergency department respiratoryviral diagnosis trends before and during the COVID-19 pandemicin Ontario, Canada. Plos one, 18(6), e0287395.

8. Vera-Valencia, G., Rendón-Macías, M. E., López-Enriquez, C.,Casillas-Casillas, M. C., Escobedo-Berumen, L., Ortega-Zárate, P.N., Silva-Ramírez, H. (2023). Impacto de la pandemia COVID-19en la prevalencia de virus que causan infecciones respiratoriasagudas en pacientes atendidos en urgencias pediátricas. RevistaMexicana de Pediatria, 90(3).

9. Peri, F., Lorenzon, B., Cason, C., Amaddeo, A., Norbedo, S., Comar,M., Cozzi, G. (2023). Urgent Hospitalizations Related to ViralRespiratory Disease in Children during Autumn and Winter Seasons2022/2023. Viruses, 15(12), 2425.

10. Audi, A., AlIbrahim, M., Kaddoura, M., Hijazi, G., Yassine, H. M.,Zaraket, H. (2020). Seasonality of respiratory viral infections: willCOVID-19 follow suit?. Frontiers in Public Health, 8, 567184.

11. Duan, Y., Jiang, M., Huang, Q., Jia, M., Yang, W., & Feng, L.(2023). Incidence, hospitalization, and mortality in children aged5 years and younger with respiratory syncytial virus‐related diseases:a systematic review and meta‐analysis