Calandria L

Language: Spanish
References: 7
Page: 38-41
PDF size: 166.93 Kb.

ABSTRACT

Peutz-Jeghers syndrome (pjs) is a rare genetic disorder characterized by hamartomatous polyposis and mucocutaneous pigmentation. The mucosal and semi-mucosal pigmented lesions, particularly in the oral cavity, affects 80-96% of individuals. There is limited literature on the treatment of the associated mucocutaneous pigmentation.
Cryosurgery using liquid nitrogen was applied in multiple sessions, soft spray was applied compared to contact tips, in separate sessions of approximately one to two months to better monitor the evolution. The contact-tip approach showing more effective and durable results, including the formation of blisters in the treated areas.
We propose cryosurgery as a treatment option for these pigmented lesions, which can cause aesthetic concerns for patients.

REFERENCES

1. Nieto JO y Pío Quintero A. Síndrome de Peutz-Jeghers. Presentaciónde casos y revisión de la literatura, Rev Col Gastroenterol 2009;24(2):188-99.

2. Jeghers H, McKusick V y Katz K, Generalized intestinal polyposiswith multiple pigmented mucocutaneous lesions, N Engl J Med1949; 241:993-1005. doi: 10.1056/NEJM194912222412501.

3. Finan MC y Ray MR, Gastrointestinal polyposis syndromes,Dermatologic Clinics 1989; 7(3):419-34. Disponible en: https://doi.org/10.1016/S0733-8635(18)30575-8.

4. Sheridan AT y Dawber RP, Laugier-Hunziker syndrome: treatmentwith cryosurgery, J Eur Acad Dermatol Venereol 1999;13(2):146-8.

5. Yuliarto D, Mawardi P y Mudigdo A, Peutz Jeghers syndrome in47 years old woman (histopathological review): case report. IndianJournal of Forensic Medicine & Toxicology 2021; 15(4):983.

6. Medeiros YL, Viana Faria L, De Souza Chandretti PC y MainentiP, Laser therapy and light sources for labial lentigines inpatients with Peutz-Jeghers syndrome, DermatTherapy 2022;35(7):e15519. Disponible en: https://doi.org/10.1111/dth.15519.

7. Yeh, CJ, Simple cryosurgical treatment of the oral melanoticmacule, Oral Surg Oral Med Oral Pathol Oral Radiol Endod2000; 90:12-3.