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Colegio de Medicina Interna de México.

2025, Number 05

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Med Int Mex 2025; 41 (05)

Neutrophil/lymphocyte ratio as a predictor of severity in patients with communityacquired pneumonia

Guzmán VAM, Morales SAL, Flores LI, Marcial CD

Language: Spanish
References: 16
Page: 268-274
PDF size: 180.21 Kb.


ABSTRACT

Objective: To report the application of the neutrophil-lymphocyte index as a predictor of severity in patients diagnosed with community-acquired pneumonia.
Materials and Methods: Epidemiologic, observational, descriptive, crosssectional, analytical, and retrospective study conducted at the General Hospital of Zone 1, Oaxaca de Juárez, between November 2022 and November 2023 in patients diagnosed with COVID-19 by RT-PCR. All enrolled patients underwent laboratory tests on admission, including a complete blood count. Study parameters: communityacquired pneumonia, pneumonia severity, neutrophil-lymphocyte ratio, age, sex, BMI, comorbidities, mortality, and length of hospital stay.
Results: Between January 2022 and December 2023, 87 patients were diagnosed with community-acquired pneumonia, 44 cases in 2022 and 43 in 2 023. Of the 87 patients, 9 died. Given the characteristics of the sample, the Kolmogorov-Smirnov test was used as a nonparametric test. The neutrophil-lymphocyte ratio was 0.433 and mortality was 0.532, with a p-value of less than 0.001, indicating a significant difference between the distributions. The comparison of these two independent groups was performed using the Kruskal-Wallis H test, with a p-value of 0.05, rejecting the working hypothesis.
Conclusions: It was found that there was no significant relationship between the neutrophil-lymphocyte ratio and the severity of community-acquired pneumonia; therefore, this ratio was not found to be useful in establishing the risk of possible complications, nor is it a complementary test for evaluating the disease or a predictor of death.


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