2025, Number 05
Pulmonary bacterial superinfections in patients with SARS-CoV-2 pneumonia in a private hospital in Mexico City
Language: Spanish
References: 24
Page: 284-290
PDF size: 194.17 Kb.
ABSTRACT
Objective: To report the prevalence of bacterial pulmonary superinfections in patients with SARS-CoV-2 pneumonia and the characteristics of those who suffer from them.Materials and Methods: This was a retrospective, observational, cross-sectional study of patients admitted to a private facility in Mexico City for SARS-CoV-2 pneumonia and bacterial superinfection between March 2020 and December 2021. Descriptive statistics and multivariate logistic regression were used to search for factors associated with mortality.
Resultads: Seventy-five cases of bacterial pulmonary superinfection in patients with percent were male, with a mean age of 62 ± 12.2 years. The most common medical conditions were systemic arterial hypertension (49.3%), obesity (40%), diabetes mellitus (34.7%), and smoking (20%). The most common microorganism identified in respiratory samples was Stenotrophomonas maltophilia (29.3%), followed by Klebsiella pneumoniae (16%). Patients who died were significantly associated with: ICU length of stay (p = 0.002), smoking history (p = 0.010), autoimmune disease (p = 0.043), obesity (p = 0.009), and the need for mechanical ventilation in 100% of decedents compared with 55.2% of survivors (p = ‹ 0.001).
Conclusions: Pulmonary bacterial superinfection may be common in patients with SARS-CoV-2 pneumonia. Patients with comorbidities associated with bacterial infection, those in critical condition, and those treated in the intensive care unit are at higher risk of death.
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