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2025, Number 4

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Acta Med 2025; 23 (4)

Perianal Merkel cell carcinoma

Gallo AB, Gallo CB, Hidalgo VC, Ibarra RJ, Aguirre TJ, Pascual GS, Pérez RE, Vilches BV
Full text How to cite this article 10.35366/120533

DOI

DOI: 10.35366/120533
URL: https://dx.doi.org/10.35366/120533

Language: Spanish
References: 5
Page: 381-383
PDF size: 218.96 Kb.


Key words:

Merkel cell carcinoma, skin cancer, metastasis, neuroendocrine carcinoma.

ABSTRACT

Introduction: Merkel cell carcinoma (MCC) is rare; it develops in areas of the skin exposed to the sun in individuals over 50 years of age. It tends to grow rapidly and metastasize at a distance. Case report: a 77-year-old male with a painless tumor in the left ischiorectal fossa. The ultrasound reported a nodule, which was resected, measuring 52.6 × 35.8 × 24.6 mm. Histopathology reported neuroendocrine carcinoma, poorly differentiated. Immunohistochemistry: compatible with CCM. Conclusion: MCC is a skin cancer of neuroendocrine origin. The treatment includes surgery, radiotherapy, and chemotherapy.


REFERENCES

  1. Patel P, Hussain K. Merkel cell carcinoma. Clin Exp Dermatol. 2021; 46 (5): 814-819.

  2. Dellambra E, Carbone ML, Ricci F, Ricci F, Di Pietro FR, Moretta G et al. Merkel cell carcinoma. Biomedicines. 2021; 9 (7): 718-721.

  3. Gauci ML, Aristei C, Becker JC, Blom A, Bataille V, Dreno B et al. Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline - Update 2022. Eur J Cancer. 2022; 171: 203-231.

  4. Farooq-Baba PU, Rasool Z, Younas-Khan I, Cockerell CJ, Wang R, Kassir M et al. Merkel cell carcinoma: from pathobiology to clinical management. Biology (Basel). 2021; 10 (12): 1293. doi: 10.3390/biology10121293.

  5. Caselli MG, Ocares UM, Benavides YC, Delgado SC, Caselli MB, García SC et al. Carcinoma de células de Merkel en la región perianal: reporte de un caso. Rev Chil Cir. 2009; 61: 378-380.




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Acta Med. 2025;23