2025, Number 1
<< Back Next >>
Rev Mex Pediatr 2025; 92 (1)
Headache and eyelid ptosis as the initial manifestation of Burkitt lymphoma
Martínez-Álvarez FJ, Calleja-Gero ML, Sirvent-Cerdá SI, Colmenero-Blanco I, Gutiérrez-Partida B, Quintero-García D, Romero-Salazar AL
Language: Spanish
References: 8
Page: 20-24
PDF size: 337.92 Kb.
ABSTRACT
Introduction: headache is a common symptom associated with a wide range of conditions. However, a thorough clinical evaluation can help identify serious underlying diseases in a timely manner.
Objective: to present the case of a pediatric patient who presented to the emergency department with headache and was ultimately diagnosed with central nervous system Burkitt lymphoma.
Case presentation: male patient aged 3 years 11 months presented with a seven-day history of headache and right eyelid ptosis, requiring hospitalization. Cranial and orbital CT imaging revealed a lesion in the sphenoid bone. A biopsy confirmed the diagnosis of Burkitt lymphoma. Despite initiation of treatment, the patient died due to infectious complications.
Conclusion: this case highlights the importance of detailed clinical history-taking and a comprehensive neurological examination in pediatric patients presenting with headache.
REFERENCES
Jeong YJ, Lee YT, Lee IG, Han JY. Primary headaches in children and adolescents - experiences at a single headache center in Korea. BMC Neurol. 2018; 18(1): 70. doi: 10.1186/s12883-018-1073-9.
Hong X, Khalife S, Bouhabel S, Bernard C, Daniel SJ, Manoukian JJ et al. Rhinologic manifestations of Burkitt Lymphoma in a pediatric population: case series and systematic review. Int J Pediatr Otorhinolaryngol. 2019; 121: 127-136. doi: 10.1016/j.ijporl.2019.03.013.
Zhao J, Hassani MA, Song J, Sun X. Primary central nervous system Burkitt's lymphoma in a pediatric patient: a case report and literature review. J Pediatr Hematol Oncol. 2024; 46(7): 375-379. doi: 10.1097/MPH.0000000000002944.
Guerra GP, Plaza LSD. Linfomas de Hodgkin y no Hodgkin. Pediatr Integral. 2021; 25(6): 308-319. Disponible en: https://www.pediatriaintegral.es/publicacion-2021-09/linfomas-de-hodgkin-y-no-hodgkin-2021/
Lateef TM, Merikangas KR, He J, Kalaydjian A, Khoromi S, Knight E et al. Headache in a national sample of American children: prevalence and comorbidity. J Child Neurol. 2009; 24(5): 536-543. doi: 10.1177/0883073808327831.
Roser T, Bonfert M, Ebinger F, Blankenburg M, Ertl-Wagner B, Heinen F. Primary versus secondary headache in children: a frequent diagnostic challenge in clinical routine. Neuropediatrics. 2013; 44(1): 34-39. doi: 10.1055/s-0032-1332743.
Rebolleda FG, Muñoz NFJ. Protocolos en neuro-oftalmología, CAO Biblioteca On Line [Internet]. 2010 [Consulta 17 julio 2025], Disponible en: https://www.oftalmologos.org.ar/catalogo/items/show/5483
Jakubowska W, Chorfi S, Bélanger C, Décarie JC, Ospina LH. Childhood Burkitt lymphoma manifesting as cavernous sinus syndrome. Can J Ophthalmol. 2022; 57(1): e22-e24. doi: 10.1016/j.jcjo.2021.06.003.