2025, Number 1
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Arch Med Urg Mex 2025; 17 (1)
Quadriceps ultrasound diagnostic performance in nutritional assessment of critically ill patients
Vargas-Miranda CE, Dector-Lira DM, Enríquez-Santos D, Mercado-Cruz E
Language: Spanish
References: 31
Page: 25-31
PDF size: 215.56 Kb.
ABSTRACT
Anthropometry, determination of basal energy expenditure, and
measurement of prealbumin and transferrin are key in nutritional assessment.
Muscle estimation, the loss of which is associated with
worse outcomes, is another component. Ultrasound is an innovative
tool for assessing muscle volume.
Objective: explore the diagnostic performance of quadriceps
measurement during nutritional assessment five days after staying
in intensive care.
Material and methods: longitudinal, prospective, observational
study. It included patients ›18 years of age in intensive care. It
excluded patients with kidney or liver disease, palliative care, pregnancy,
puerperium, and those unable to perform measurements.
Prealbumin, transferrin, and quadriceps thickness were measured by
ultrasound upon admission and five days later. ROC curves were
performed and sensitivity, specificity, positive predictive value (PPV),
and negative predictive value (NPV) were calculated. p
≤ 0.05 was
considered significant.
Results: eighty patients were included. Age was 58.5 (51-68)
years. Decreased quadriceps thickness (›3 mm) had a sensitivity of
30.8%, specificity of 73.3%, PPV of 83.3%, and NPV of 19.6%. The
area under the curve was 0.52 (p=0.08).
Conclusion: ultrasound has a low diagnostic yield and should
not be used alone to diagnose malnutrition in critically ill patients. It
may be useful as a complement to other assessments.
REFERENCES
Reignier J, Rice TW, Arabi YM, Casaer M. Nutritional Support inthe ICU. BMJ [Internet]. 2025 Jan 2;e077979. Available from: https://www.bmj.com/lookup/doi/10.1136/bmj-2023-077979
Singer P, Blaser AR, Berger MM, Calder PC, Casaer M, HiesmayrM, et al. ESPEN practical and partially revised guideline: Clinicalnutrition in the intensive care unit. Clinical Nutrition. 2023 Sep1;42(9):1671–89.
Wischmeyer PE, Bear DE, Berger MM, De Waele E, Gunst J, Mc-Clave SA, et al. Personalized nutrition therapy in critical care: 10expert recommendations. Crit Care. 2023 Dec 1;27(1).
Zusman O, Theilla M, Cohen J, Kagan I, Bendavid I, Singer P.Resting energy expenditure, calorie and protein consumption incritically ill patients: A retrospective cohort study. Crit Care. 2016Nov 10;20(1).
Achamrah N, Delsoglio M, De Waele E, Berger MM, Pichard C. Indirectcalorimetry: The 6 main issues. Clinical Nutrition. 2021 Jan1;40(1):4–14.
Delsoglio M, Achamrah N, Berger MM, Pichard C. Indirect calorimetryin clinical practice. J Clin Med. 2019 Sep 1;8(9).
Frankenfield DC, Ashcraft CM, Galvan DA. Prediction of restingmetabolic rate in critically ill patients at the extremes of bodymass index. Journal of Parenteral and Enteral Nutrition. 2013May;37(3):361–7.
Ridley EJ, Parke RL, Davies AR, Bailey M, Hodgson C, DeaneAM, et al. What Happens to Nutrition Intake in the Post–IntensiveCare Unit Hospitalization Period? An Observational Cohort Studyin Critically Ill Adults. Journal of Parenteral and Enteral Nutrition.2019 Jan 1;43(1):88–95.
Cardenas D, Correia MITD, Ochoa JB, Hardy G, Rodriguez-VentimillaD, Bermúdez CE, et al. Clinical Nutrition and Human Rights.An International Position Paper. Nutrition in Clinical Practice. 2021Jun 1;36(3):534–44.
Kondrup J, Allison SP, Elia M, Vellas B, Plauth M. ESPEN guidelinesfor nutrition screening 2002. Clinical Nutrition. 2003;22(4):415–21.
Merriweather J, Smith P, Walsh T. Nutritional rehabilitation afterICU - does it happen: A qualitative interview and observationalstudy. J Clin Nurs. 2014;23(5–6):654–62.
Ranasinghe RNK, Biswas M, Vincent RP. Prealbumin: The clinicalutility and analytical methodologies. Ann Clin Biochem. 2022 Jan1;59(1):7–14.
Armour Forse R, And HM, Siiizcal FACS. Clinical Research SerumAlbumin and Nutritional Status. JOURNAL OF PARESTERALAND ENTERAL NUTRITION. 1980 Jun;4:1–5.
Roza AM, Tuitt D, Shizgal HM. Transferrin - A Poor Measure ofNutritional Status. journal of parenteral and enteral nutrition. 1984Feb 16;8.
Wischmeyer PE. Tailoring nutrition therapy to illness and recovery.Crit Care. 2017 Dec 28;21.
Papadopoulou SK, Voulgaridou G, Kondyli FS, Drakaki M, SianidouK, Andrianopoulou R, et al. Nutritional and Nutrition-RelatedBiomarkers as Prognostic Factors of Sarcopenia, and Their Rolein Disease Progression. Diseases. 2022 Sep 1;10(3).
Mourtzakis M, Wischmeyer P. Bedside ultrasound measurementof skeletal muscle. Curr Opin Clin Nutr Metab Care.2014;17(5):389–95.
Mourtzakis M, Parry S, Connolly B, Puthucheary Z. Skeletal muscleultrasound in critical care: A tool in need of translation. Ann AmThorac Soc. 2017 Oct 1;14(10):1495–503.
Fischer A, Anwar M, Hertwig A, Hahn R, Pesta M, Timmermann I,et al. Ultrasound method of the USVALID study to measure subcutaneousadipose tissue and muscle thickness on the thigh andupper arm: An illustrated step-by-step guide. Clin Nutr Exp. 2020Aug 1;32:38–73.
Fischer A, Anwar M, Hertwig A, Hahn R, Pesta M, Timmermann I,et al. Ultrasound method of the USVALID study to measure subcutaneousadipose tissue and muscle thickness on the thigh andupper arm: An illustrated step-by-step guide. Clin Nutr Exp. 2020Aug 1;32:38–73.
Rustani K, Kundisova L, Capecchi PL, Nante N, Bicchi M. Ultrasoundmeasurement of rectus femoris muscle thickness as a quickscreening test for sarcopenia assessment. Arch Gerontol Geriatr.2019 Jul 1;83:151–4.
Lambell KJ, Tatucu-Babet OA, Chapple LA, Gantner D, Ridley EJ.Nutrition therapy in critical illness: A review of the literature for clinicians.Crit Care. 2020 Feb 4;24(1).
Van Zanten ARH, De Waele E, Wischmeyer PE. Nutrition therapyand critical illness: Practical guidance for the icu, post-icu, andlong-term convalescence phases. Crit Care. 2019 Nov 21;23(1).
Cederholm T, Jensen GL, Correia MITD, Gonzalez MC, FukushimaR, Higashiguchi T, et al. GLIM criteria for the diagnosis ofmalnutrition – A consensus report from the global clinical nutritioncommunity. Clinical Nutrition. 2019 Feb 1;38(1):1–9.
Mallampalli A, Mcclave SA. Monitoring Patients on Enteral TubeFeeds. Tech Gastrointest Endosc. 2001 Jun;3:55–61.
Wu C, Wang X, Yu W, Tian F, Liu S, Li P, et al. Hypermetabolism inthe Initial Phase of Intensive Care Is Related to a Poor Outcome inSevere Sepsis Patients. Ann Nutr Metab. 2015 Aug 20;66(4):188–95.
Sanz-Paris A, González-Fernandez M, Hueso-Del Río LE, Ferrer-Lahuerta E, Monge-Vazquez A, Losfablos-Callau F, et al.Muscle thickness and echogenicity measured by ultrasound coulddetect local sarcopenia and malnutrition in older patients hospitalizedfor hip fracture. Nutrients. 2021 Jul 1;13(7).
Berger J, Bunout D, Barrera G, de la Maza MP, Henriquez S, LeivaL, et al. Rectus femoris (RF) ultrasound for the assessmentof muscle mass in older people. Arch Gerontol Geriatr. 2015 Jul1;61(1):33–8.
Sions JM, Velasco TO, Teyhen DS, Hicks GE. Ultrasound imaging:Intraexaminer and interexaminer reliability for multifidus musclethickness assessment in adults aged 60 to 85 years versus youngeradults. Journal of Orthopaedic and Sports Physical Therapy.2014;44(6):425–34.
Cabrera AG, Sanz-Lorente M, Sanz-Valero J, López-Pintor E.Compliance and adherence to enteral nutrition treatment in adults:A systematic review. Nutrients. 2019 Nov 1;11(11).
Wanden-Berghe C, Patino-Alonso MC, Galindo-Villardón P,Sanz-Valero J. Complications associated with enteral nutrition:CAFANE study. Nutrients. 2019 Sep 1;11(9).