Ramírez AC, Domínguez GLG, Domínguez CLG

Language: Spanish
References: 5
Page: 486-488
PDF size: 240.70 Kb.

Bizarre parostal osteochondromatous proliferation, or Nora's Lesion, is a rare bone lesion described by Nora et al. in 1983 that affects the tubular bones of hands and feet. Ten years later, Meneses reported it in 17 long bones. In 2014, Kapukaya, in a systematic study, reported 43 cases with an age range from 10 to 53 years), with no difference between genders. The affected bones were the femur (25%), ulna (23%), and tibia (n = 6), of which five were in the proximal metaphysis; it has been reported in the radius, humerus, fibula, and clavicle.

REFERENCES

1. Nora FE, Dahlin DC, Beabout JW. Bizarre parosteal osteochondromatous proliferations of the hands and feet. Am J Surg Pathol. 1983; 7 (3): 245-250.

2. Meneses MF, Unni KK, Swee RG. Bizarre parosteal osteochondromatous proliferation of bone (Nora's lesion). Am J Surg Pathol. 1993; 17 (7): 691-697.

3. Kapukaya A, Alemdar C, Isik R, Yavuz UB, Azboy I, Gem M et al. Bizarre parosteal osteochondromatous proliferation of long bones: two new cases and literature study. J Med Cases. 2014; 5 (6): 315-325.

4. Nilsson M, Domanski HA, Mertens F, Mandahl N. Molecular cytogenetic characterization of recurrent translocation breakpoints in bizarre parosteal osteochondromatous proliferation (Nora's lesion). Hum Pathol. 2004; 35 (9): 1063-1069.

5. Gitto S, Serpi F, Messina C, Albano D, Di Bernardo A, Armiraglio E et al. Bizarre parosteal osteochondromatous proliferation: an educational review. Insights Imaging. 2023; 14 (1): 109. doi: 10.1186/s13244-023-01455-0.