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Federación Mexicana de Ginecología y Obstetricia, A.C.

2025, Number 7

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Ginecol Obstet Mex 2025; 93 (7)

Takayasu arteritis in pregnancy: perinatal outcome in a infrequent disease

Ávila JMA, Montiel MRI, Ruz SGM

Language: Spanish
References: 23
Page: 241-248
PDF size: 417.64 Kb.


ABSTRACT

Objectivo: to describe the evolution of pregnant patients diagnosed with Takayasu arteritis and their respective perinatal outcomes.
Methodology: This observational, cross-sectional, descriptive study was conducted from January 1, 2021, to January 1, 2025, among pregnant patients diagnosed with Takayasu arteritis who were treated at the Doctor Agustín O'Horán General Hospital in Mérida, Yucatán.
Results: Three patients were Clinical Case 1: 18-year-old primigravida with a previous diagnosis of type IIa Takayasu arteritis at age 17. Prior to this, she had undergone treatment with steroids, immunosuppressants, nifedipine, and a stent one month after the diagnosis of the disease. The patient was admitted to the hospital at 33 weeks of pregnancy, with no prior prenatal care. Clinical Case 2: A 23-year-old patient, who is a primigravida, was diagnosed with the disease at age 18. She has previously undergone treatment with prednisone and two stents. She was admitted to the hospital at 33.1 weeks of pregnancy, with no prior prenatal care. Clinical Case 3: The patient is a 22-year-old female who was diagnosed with type V Takayasu arteritis at age 15. She has previously received treatment with prednisone. Her additional diagnoses include aortic coarctation, mesenteric artery aneurysm, and a brachial plexus injury due to introducer retention in the humeral artery. She has undergone seven surgical procedures, but no cardiological follow-up was conducted.The patient was admitted to the hospital at 32.4 weeks of pregnancy. She had received six prenatal check-ups at a health center, but had not been referred to a tertiary care center or evaluated by a cardiologist.
Conclusion: Given the prevalence of Takayasu's disease among women of childbearing age, it is crucial to understand the implications of its occurrence during pregnancy and the associated perinatal outcomes. It is essential for healthcare professionals to possess a comprehensive understanding of the clinical course, diagnosis, treatment, and multidisciplinary monitoring to ensure the survival of these patients.


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