Bazo-Medina JM, Castaño-Guerra RJ, Ayala-Hernández E, Camacho-Bernal R

Language: Spanish
References: 13
Page: 172-179
PDF size: 1389.73 Kb.

ABSTRACT

Acute graft failure occurs in approximately 30% of heart transplant recipients and remains the leading cause of early post-transplant mortality during the immediate postoperative period. This entity is multifactorial; the diverse underlying etiologies can be categorized according to their predominant pathophysiologic mechanism and temporality (recipient selection, donor selection, surgical procedure, and perioperative events). Although definitions vary slightly across series, most authors agree that the clinical syndrome is characterized by the onset of manifestations within the first 24 hours post-transplant. The clinical phenotype can be subclassified according to the predominant hemodynamic compromise, and severity stratification drives both therapeutic decision-making and prognostication. We present the case of a male patient with advanced heart failure from a dedicated Heart Failure Program who underwent orthotopic heart transplantation. His initially unfavorable post-transplant course, followed by complete recovery, illustrates a representative clinical scenario of this complication.

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