Samperio PC, Orozco GA

Language: Spanish
References: 11
Page: 98-101
PDF size: 199.23 Kb.

ABSTRACT

The purpose of this study was to analyze the complications of intrauterine growth restriction, both moderate and severe, in newborns weighing less than 2.5 kg. A retrospective study was carried out with a review of clinical records from the Hospital Angeles Pedregal of newborns weighing less than 2.5 kg, over a period of three years. The following data were collected: gestational age, weight, and sex. These data were classified according to the degree of intrauterine restriction. The frequency of IUR in the study population was analyzed, as well as the presence of acute complications, Hypothermia, the need for oxygen administration, multifactorial hyperbilirubinemia, and sepsis. An analysis of the results was carried out using descriptive and analytical statistics, using means, standard deviation, and the p-test. The results were found from 101 patients studied: Hypothermia (21.2%), with severe IUGR, and (11.4%) with moderate IUGR. Hypoglycemia (7%), oxygen administration to 20 patients (8%) had severe IUGR, and 29% moderate IUGR, hyperbilirubinemia in two patients, and one patient had early neonatal sepsis. The acute complications of intrauterine growth restriction are diverse and can have a significant impact on perinatal morbidity and mortality; those found were respiratory, metabolic, and infectious.

REFERENCES

1. Pels A, Beune IM, van Wassenaer-Leemhuis AG, Limpens J, Ganzevoort W. Early-onset fetal growth restriction: A systematic review on mortality and morbidity. Acta Obstet Gynecol Scand. 2020; 99 (2): 153-166. doi: 10.1111/aogs.13702.

2. Monier I, Ego A, Hocquette A, Benachi A, Goffinet F, Lelong N et al. Validity of a Delphi consensus definition of growth restriction in the newborn for identifying neonatal morbidity. Am J Obstet Gynecol. 2025; 232 (2): 224.e1-224.e13. doi: 10.1016/j.ajog.2024.04.033.

3. Engineer N, Kumar S. Perinatal variables and neonatal outcomes in severely growth restricted preterm fetuses. Acta Obstet Gynecol Scand. 2010; 89 (9): 1174-1181. doi: 10.3109/00016349.2010.501370.

4. Rosenberg A. The IUGR newborn. Semin Perinatol. 2008; 32 (3): 219-224. doi: 10.1053/j.semperi.2007.11.003.

5. Yu VY, Upadhyay A. Neonatal management of the growth-restricted infant. Semin Fetal Neonatal Med. 2004; 9 (5): 403-409. doi: 10.1016/j.siny.2004.03.004.

6. Karapati E, Sokou R, Iliodromiti Z, Tsaousi M, Sulaj A, Tsantes AG et al. Assessment of hemostatic profile in neonates with intrauterine growth restriction: a systematic review of literature. Semin Thromb Hemost. 2024; 50 (2): 169-181. doi: 10.1055/s-0043-1762893.

7. Longo S, Bollani L, Decembrino L, Di Comite A, Angelini M, Stronati M. Short-term and long-term sequelae in intrauterine growth retardation (IUGR). J Matern Fetal Neonatal Med. 2013; 26 (3): 222-225. doi: 10.3109/14767058.2012.715006.

8. Ellis M, Manandhar N, Shakya U, Manandhar DS, Fawdry A, Costello AM. Postnatal hypothermia and cold stress among newborn infants in Nepal monitored by continuous ambulatory recording. Arch Dis Child Fetal Neonatal Ed. 1996; 75 (1): F42-F45. doi: 10.1136/fn.75.1.f42.

9. Bahia MLR, Velarde GC, Silva FCD, Araujo Júnior E, Sá RAM. Adverse perinatal outcomes in fetuses with severe late-onset fetal growth restriction. J Matern Fetal Neonatal Med. 2022; 35 (25): 8666-8672. doi: 10.1080/14767058.2021.1995858.

10. Horgan R, Nehme L, Jensen HJ, Shah AP, Saal R, Onishi K et al. Neonatal outcomes among fetuses with an abdominal circumference <3rd %ile and estimated fetal weight 3rd to 9th %ile compared to fetuses with an EFW <3rd %ile. Am J Perinatol. 2024; 41 (9): 1120-1125. doi: 10.1055/a-2259-0148.

11. Abbas G, Shah S, Hanif M, Shah A, Rehman AU, Tahir S et al. The frequency of pulmonary hypertension in newborn with intrauterine growth restriction. Sci Rep. 2020; 10 (1): 8064. doi: 10.1038/s41598-020-65065-2.