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2026, Number 1

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Cardiovasc Metab Sci 2026; 37 (1)

Clinical features, echocardiographic findings and surgical aspects related to mortality in complicated endocarditis

Bazo-Medina JM, Castaño-Guerra RJ

Language: English
References: 17
Page: 9-20
PDF size: 2874.81 Kb.


ABSTRACT

Infective Endocarditis is a serious public health problem with high morbidity and mortality, and a considerable prevalence in our setting. International guidelines for the diagnosis and treatment of endocarditis consider clinical, laboratory, and imaging criteria to define this entity and establish recommendations for its management. Global mortality is estimated around 20%; however, there is no information available on the epidemiology or prognosis in Mexico. An important finding among patients at our centre is the incidence of cases with local complications. Naturally, as anatomical complexity increases, surgery becomes more challenging, so local complications are expected to directly influence the risk of perioperative death. The purpose of this study was to identify risk factors associated with echocardiographic complications in patients diagnosed with Infective Endocarditis (IE) at tertiary level public hospital, as well as to evaluate their postoperative outcome. This information could contribute to a better understanding of IE and facilitate more timely treatment. Over a five-year period, 60 patients were included, with an incidence of local complications of 73.3%. No variables were significantly associated with the development of local complications. However, type 2 diabetes (p = 0.03), heart failure (p = 0.01), and prosthetic valves (p = 0.03) were risk factors associated with mortality. Regarding clinical scenario, uncontrolled sepsis (p = 0.02), septic shock (p = 0.01) and multiple organ failure (p = 0.001) at the time of IE diagnosis and after surgery, had higher mortality (p = 0.02).


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