2026, Number 1
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Rev Mex Cir Bucal Maxilofac 2026; 22 (1)
Functional palatal closure in cleft palate: surgical and anatomical-functional determinants. Analysis of the available evidence
Castilla CH, Dolores GIA, Salgado CF
Language: Spanish
References: 31
Page: 12-20
PDF size: 520.46 Kb.
ABSTRACT
Introduction: cleft palate is a congenital malformation associated with speech, swallowing, and middle ear ventilation disorders. Despite advances in palatoplasty, velopharyngeal insufficiency remains one of the main functional sequelae. In this context, functional palatal closure has gained relevance as a surgical objective beyond anatomical repair.
Objective: to analyze the available evidence on surgical and anatomical-functional determinants associated with functional palatal closure in pediatric patients with non-syndromic cleft palate, with emphasis on timing of palatoplasty, surgical technique, and its velopharyngeal and auditory implications.
Material and methods: a structured narrative review was conducted in PubMed, Scopus, and ScienceDirect, including publications from 2000 to 2024 on surgical timing, palatoplasty technique, velopharyngeal function, and auditory outcomes in pediatric patients with non-syndromic cleft palate.
Results: fifteen studies were analyzed. Palatoplasty performed before nine months of age was associated with a lower incidence of velopharyngeal insufficiency than surgery performed after the first year of life. Techniques involving active muscular reconstruction of the soft palate, particularly the Furlow technique, showed better functional outcomes than Bardach or von Langenbeck. Greater velar length was associated with improved velopharyngeal competence. Evidence regarding auditory outcomes was less consistent, although it suggests a possible benefit from adequate muscular reconstruction.
Conclusions: functional palatal closure depends on the interaction between surgical timing, repair technique, and anatomical-functional restoration of the velar musculature.
REFERENCES
Weissler EH, Paine KM, Ahmed MK, Taub PJ. Alveolar bone grafting and cleft lip and palate: a review. Plast Reconstr Surg. 2016; 138 (6): 1287-1295.
Rossell-Perry P. Atlas of operative techniques in primary cleft lip and palate repair. Cham: Springer; 2020. p. 400.
Shetye PR. Facial growth of adults with unoperated clefts. Clin Plast Surg. 2004; 31 (2): 361-371.
Kummer AW. Speech evaluation for patients with cleft palate. Clin Plast Surg. 2014; 41 (2): 241-251.
Poff C, Horton J, Boerner R, Marston AP, Nguyen SA, White DR. Publishing trends in velopharyngeal insufficiency. Int J Pediatr Otorhinolaryngol. 2020; 129: 109761.
Phalke N, Goldman JJ. Cleft palate. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025.
Prosak OL, Du J, Gao L, Patel KR, Zhao S, Braun S et al. Does palatoplasty technique impact resolution of eustachian tube dysfunction? Cleft Palate Craniofac J. 2025; 62 (2): 179-187.
Widodo DW, Hisyam A, Alviandi W, Mansyur M. Comparison of eustachian tube ventilation function between cleft palate and normal patients using sonotubometry. JPRAS Open. 2021; 29: 32-40.
Cornefjord M, Arnebrant K, Guné H, Holst J, Klinto K, Stiernman M et al. A systematic review of differences in outcome between one and two stage palate repair in cleft lip and palate. J Plast Surg Hand Surg. 2023; 58: 132-141.
Mir MA, Manohar N, Chattopadhyay D, Mahakalkar SS. A novel modification of Bardach's two-flap palatoplasty for repair of a difficult cleft palate. Arch Plast Surg. 2021; 48 (1): 75-79. doi: 10.5999/aps.2020.00416.
Alter N, Stone A, Powell M, Gordon EJ, Anan B, Hamdan U et al. It's time to define the global burden of velopharyngeal insufficiency. Cleft Palate Craniofac J. 2026; 63 (4): 945-948.
Shaw W, Semb G, Lohmander A, Persson C, Willadsen E, Clayton-Smith J et al. Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age. BMJ Open. 2019; 9 (7): e029780. doi: 10.1136/bmjopen-2019-029780.
Reddy RR, Gosla-Reddy S, Chilakalapudi A, Kokali S, Bronkhorst EM, Kummer AW et al. Effect of one-stage versus two-stage palatoplasty on hypernasality and fistula formation in children with complete unilateral cleft lip and palate: a randomized controlled trial. Plast Reconstr Surg. 2018; 142 (1): 42e-50e. doi: 10.1097/PRS.0000000000004486.
Sullivan SR, Marrinan EM, LaBrie RA, Rogers GF, Mulliken JB. Palatoplasty outcomes in nonsyndromic patients with cleft palate: a 29-year assessment of one surgeon's experience. J Craniofac Surg. 2009; 20 Suppl 1: 612-616. doi: 10.1097/SCS.0b013e318192801b.
Becker M, Svensson H, Sarnas KV, Jacobsson S. Von Langenbeck or Wardill procedures for primary palatal repair in patients with isolated cleft palate--speech results. Scand J Plast Reconstr Surg Hand Surg. 2000; 34 (1): 27-32. doi: 10.1080/02844310050160141.
Plonkowski AT, Choi DG, Naidu P, Turk M, Yao CA, Magee WP 3rd. The rate of secondary speech surgery after cleft palate repair: a systematic review. Plast Reconstr Surg Glob Open. 2025; 13 (2): e6465. doi: 10.1097/GOX.0000000000006465.
Moreau A, Charpuis-Vandenbogaerde C, Neiva-Vaz C, Sanquer E, Soupre V, Vazquez MP et al. Speech outcome after intravelar veloplasty. J Stomatol Oral Maxillofac Surg. 2021; 122 (2): 147-150. doi: 10.1016/j.jormas.2020.05.015.
Pitkanen VV, Geneid A, Saarikko AM, Hakli S, Alaluusua SA. Diagnosing and managing velopharyngeal insufficiency in patients with cleft palate after primary palatoplasty. J Craniofac Surg. 2025; 36 (3): 1008-1016. doi: 10.1097/SCS.0000000000009822.
Gong SW, Hung P, Obinero CG, Barrera J, Jiang ZY, Greives MR et al. Effect of palatoplasty technique on otologic outcomes in children with cleft palate. Am J Otolaryngol. 2025; 46 (3): 104610. doi: 10.1016/j.amjoto.2025.104610.
Pasick CM, Shay PL, Stransky CA, Solot CB, Cohen MA, Jackson OA. Long term speech outcomes following late cleft palate repair using the modified Furlow technique. Int J Pediatr Otorhinolaryngol. 2014; 78 (12): 2275-2280. doi: 10.1016/j.ijporl.2014.10.033.
Téblick S, Ruymaekers M, Van de Casteele E, Nadjmi N. Effect of cleft palate closure technique on speech and middle ear outcome: a systematic review. J Oral Maxillofac Surg. 2019; 77 (2): 405.e1-405.e15. doi: 10.1016/j.joms.2018.09.027.
Kummer AW. Cleft palate and craniofacial conditions: a comprehensive guide to clinical management. 4th ed. Burlington, MA: Jones & Bartlett Learning; 2020.
Perry JL. Anatomy and physiology of the velopharyngeal mechanism. Semin Speech Lang. 2011; 32 (2): 83-92. doi: 10.1055/s-0031-1277712.
Álvarez-Carvajal DC, Inostroza-Allende F, Geldres-Meneses MB, Giugliano-Villarroel C. Speech outcomes and velopharyngeal function in children undergoing submucous cleft palate repair. J Craniofac Surg. 2023; 34 (6): e597-e600. doi: 10.1097/SCS.0000000000009570.
Smetona JT, Naran S, Ford M, Losee JE. What's new in cleft palate and velopharyngeal dysfunction management: An update. Plast Reconstr Surg. 2024; 154 (2): 378e-390e. doi: 10.1097/PRS.0000000000011312.
Huang Z, Bo Z, Li J, Zheng Q, Shi B, Zeng N. Proposed clinical model for predicting speech outcomes in patients undergoing Furlow palatoplasty for velopharyngeal insufficiency after primary palatoplasty. J Craniomaxillofac Surg. 2024; 52 (2): 234-239. doi: 10.1016/j.jcms.2023.12.007.
Ha S, Koh KS, Moon H, Jung S, Oh TS. Clinical outcomes of primary palatal surgery in children with nonsyndromic cleft palate with and without lip. Biomed Res Int. 2015; 2015: 185459. doi: 10.1155/2015/185459.
Shaffer AD, Ford MD, Losee JE, Goldstein J, Costello BJ, Grunwaldt LJ et al. The association between age at palatoplasty and speech and language outcomes in children with cleft palate: an observational chart review study. Cleft Palate Craniofac J. 2020; 57 (2): 148-160. doi: 10.1177/1055665619882566.
Gamble C, Persson C, Willadsen E, Albery L, Soegaard Andersen H, Zattoni Antoneli M et al. Timing of primary surgery for cleft palate. N Engl J Med. 2023; 389(9): 795-807. doi: 10.1056/NEJMoa2215162.
Hofman L, Paes EC, Haverkamp SJ, Jenniskens K, Mink van der Molen AB. "Long term speech outcomes after using the Sommerlad technique for primary palatoplasty: a retrospective study in the Wilhelmina Children's Hospital, Utrecht". Clin Oral Investig. 2024; 28 (8): 441. doi: 10.1007/s00784-024-05828-7.
Michael P, Karnell. Instrumental assessment of velopharyngeal closure for speech. Semin Speech Lang. 2011; 32 (2): 168-178. doi: 10.1055/s-0031-1277719.